Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937820 | 0.92 | PTGDR2 (0.58) | PTGDR2TP53ALDH1A1KDM4ESTAT3 | |
| SCHEMBL3931978 | 0.89 | MEN1 (0.54) | PTGDR2TP53ALDH1A1KDM4ESTAT3 | |
| SCHEMBL3937365 | 0.88 | PTGDR2 (0.53) | PTGDR2TP53ALDH1A1KDM4ESTAT3 | |
| SCHEMBL3928788 | 0.88 | PTGDR2 (0.63) | PTGDR2ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3932364 | 0.87 | PTGDR2 (0.55) | PTGDR2TP53ALDH1A1KDM4ESTAT3 | |
| SCHEMBL14367479 | 0.86 | KMT2A (0.43) | PTGDR2ALDH1A1SMN1; SMN2KMT2AGAA | |
| SCHEMBL3929256 | 0.85 | PTGDR2 (0.58) | PTGDR2TP53ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL3929213 | 0.85 | MEN1 (0.50) | PTGDR2TP53ALDH1A1KDM4ESTAT3 | |
| SCHEMBL3928769 | 0.85 | PTGDR2 (0.61) | PTGDR2TP53ALDH1A1KDM4ESTAT3 | |
| SCHEMBL3929149 | 0.85 | PTGDR2 (0.51) | PTGDR2TP53ALDH1A1KDM4ESTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101490024-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | claimed |
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | claimed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | claimed |
| CN-101490024-A | Substituted phenylacetic acids as DP-2 antagonists | ICOS CORP (US) | 2009-07-22 | — | — | CN | disclosed |
| EP-2044044-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |