Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933952 | 0.86 | PTGDR2 (0.58) | KMT2ASMN1; SMN2PTGDR2GAAALDH1A1 | |
| SCHEMBL3936575 | 0.81 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1PTGDR2CRHBP | |
| SCHEMBL3937820 | 0.78 | PTGDR2 (0.58) | KMT2ASMN1; SMN2MEN1PTGDR2GAA | |
| SCHEMBL3931978 | 0.75 | MEN1 (0.54) | KMT2ASMN1; SMN2MEN1PTGDR2ALDH1A1 | |
| SCHEMBL3937365 | 0.74 | PTGDR2 (0.53) | KMT2ASMN1; SMN2MEN1PTGDR2CRHBP | |
| SCHEMBL3937915 | 0.73 | ALDH1A1 (0.51) | KMT2ASMN1; SMN2MEN1PTGDR2GAA | |
| SCHEMBL3929086 | 0.73 | KMT2A (0.55) | KMT2ASMN1; SMN2MEN1GAAALDH1A1 | |
| SCHEMBL3928788 | 0.73 | PTGDR2 (0.63) | SMN1; SMN2PTGDR2ALDH1A1 | |
| SCHEMBL3932364 | 0.73 | PTGDR2 (0.55) | KMT2ASMN1; SMN2MEN1PTGDR2GAA | |
| SCHEMBL4151340 | 0.71 | FFAR1 (0.49) | S1PR1S1PR5PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143745-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-13 | — | — | WO | disclosed |