Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 3/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 2/20 | 0.41 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2844611 | 0.86 | LMNA (0.43) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL25748480 | 0.83 | LMNA (0.45) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| Bromide SCHEMBL28479572 | 0.80 | LMNA (0.42) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL2843576 | 0.80 | LMNA (0.44) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31571724 | 0.80 | LMNA (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31571723 | 0.80 | LMNA (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL31571722 | 0.80 | LMNA (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28544833 | 0.80 | LMNA (0.47) | LMNAALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL8746175 | 0.79 | TSHR (0.47) | LMNATSHRPLA2G1BDNM1PLA2G2A | |
| SCHEMBL6452480 | 0.79 | TSHR (0.47) | LMNATSHRPLA2G1BDNM1PLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |