SCHEMBL2843576

SCHEMBL2843576

CCCCCC(N(C)C)N(CCCO)CCCO

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
TSHR P16473 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.41
PLA2G1B P04054 3/20 0.39
PSMD14 O00487 2/20 0.39
MMP2 P08253 2/20 0.39
ATG4B Q9Y4P1 2/20 0.39
HSP90AA1 P07900 1/20 0.39
RAD52 P43351 1/20 0.39
DNM1 Q05193 4/20 0.37
CYP2D6 P10635 2/20 0.36
PLA2G2A P14555 1/20 0.36
SPHK1 Q9NYA1 1/20 0.36
GMNN O75496 1/20 0.36
POLB P06746 1/20 0.36
THPO P40225 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2844611 0.90 LMNA (0.43) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL2842761 0.85 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL28639819 0.84 DNM1 (0.42) LMNATSHRPLA2G1BDNM1PLA2G2A
SCHEMBL3934073 0.80 LMNA (0.45) LMNAALDH1A1HSD17B10MEN1KMT2A
Hydrochloric Acid SCHEMBL10492556 0.80 DNM1 (0.48) TSHRPLA2G1BDNM1PLA2G2A
SCHEMBL2842756 0.79 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2MAPT
Fluoride SCHEMBL11099490 0.78 LMNA (0.46) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL11449797 0.78 LMNA (0.46) LMNAALDH1A1HSD17B10MEN1KMT2A
SCHEMBL4187850 0.77 PLA2G1B (0.47) LMNATSHRPLA2G1BDNM1PLA2G2A
SCHEMBL29286448 0.77 LMNA (0.44) LMNAALDH1A1HSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1092737-B1 Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin TOSOH CORP (JP) 2003-09-24 EP claimed
US-6596663-B1 Reacting a polyol with an organic polyisocyanate in the presence of a diamine catalyst and, if necessary, a blowing agent, a surfactant, a cross-linking agent TOSOH CORPORATION (JP) 2003-07-22 US claimed
EP-1092737-A2 Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin Tosoh Corporation (JP) 2001-04-18 EP claimed
US-20240255403-A1 POLYURETHANE-CONTAINING NON-FOAMED MOLDED BODY CANON KABUSHIKI KAISHA (JP) 2024-08-01 US disclosed
EP-4397466-A1 POLYURETHANE-CONTAINING NON-FOAMED MOLDED BODY CANON KABUSHIKI KAISHA (JP) 2024-07-10 EP disclosed
WO-2023032827-A1 POLYURETHANE-CONTAINING NON-FOAMED MOLDED BODY キヤノン株式会社 2023-03-09 WO disclosed
US-8877825-B2 Catalyst composition for production of polyurethane resin and method for producing polyurethane resin TOSOH CORPORATION (JP) 2014-11-04 US disclosed
EP-2050775-B1 CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN TOSOH CORP (JP) 2013-08-14 EP disclosed
US-20100130629-A1 CATALYST COMPOSITION FOR PRODUCTION OF POLYURETHANE RESIN AND METHOD FOR PRODUCING POLYURETHANE RESIN (AS AMENDED) TOSOH CORPORATION (JP) 2010-05-27 US disclosed
EP-2050775-A1 CATALYST COMPOSITION FOR POLYURETHANE RESIN PRODUCTION AND METHOD FOR PRODUCING POLYURETHANE RESIN Tosoh Corporation (JP) 2009-04-22 EP disclosed
EP-1092737-B1 Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin TOSOH CORP (JP) 2003-09-24 EP disclosed
US-6596663-B1 Reacting a polyol with an organic polyisocyanate in the presence of a diamine catalyst and, if necessary, a blowing agent, a surfactant, a cross-linking agent TOSOH CORPORATION (JP) 2003-07-22 US disclosed
EP-1092737-A2 Catalyst composition for the production of a polyurethane resin, and method for producing a polyurethane resin Tosoh Corporation (JP) 2001-04-18 EP disclosed