Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 20/20 | 0.69 |
| ▸ | CTSL | P07711 | 19/20 | 0.69 |
| ▸ | CTSS | P25774 | 18/20 | 0.69 |
| ▸ | CTSV | O60911 | 1/20 | 0.67 |
| ▸ | CTSB | P07858 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4310385 | 1.00 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4323805 | 1.00 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4316429 | 1.00 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4312951 | 1.00 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4314612 | 0.89 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL5983017 | 0.88 | CTSK (0.69) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4318828 | 0.87 | CTSK (0.70) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6744240 | 0.87 | CTSK (0.70) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL21067433 | 0.84 | CTSK (0.68) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4171722 | 0.84 | CTSK (0.68) | CTSKCTSLCTSSCTSVCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090253904-A1 | Process for the Preparation of a Tetrahydro-1H-Azepines | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2009-10-08 | — | — | US | disclosed |
| EP-2044030-A1 | PROCESS FOR THE PREPARATION OF A TETRAHYDRO-1H-AZEPINES | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009671-A1 | PROCESS FOR THE PREPARATION OF A TETRAHYDRO-1H-AZEPINES | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253904-A1 | Process for the Preparation of a Tetrahydro-1H-Azepines | DHPS, CYP1A1, POR | CTSK 2636/4885CTSL 4206/4885CTSS 2581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.