SCHEMBL393445

SCHEMBL393445

O=C(Cl)OC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.50
FABP5 Q01469 3/20 0.49
FABP7 O15540 2/20 0.49
EPHX2 P34913 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
MDM4 O15151 1/20 0.40
TP53 P04637 1/20 0.40
CASP3 P42574 2/20 0.39
HTR2A P28223 1/20 0.39
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30396315 1.00 KMT2A (0.50) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL15058849 0.90 KMT2A (0.55) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL27547 0.86 KMT2A (0.55) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29349891 0.86 KMT2A (0.55) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL44676 0.86 KMT2A (0.58) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL29598813 0.85 FABP5 (0.54) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL7767154 0.85 FABP5 (0.54) KMT2AFABP5FABP7EPHX2CA1
Ammonia Solution, Strong SCHEMBL27794450 0.85 KMT2A (0.54) KMT2AFABP5FABP7EPHX2CA1
Hydrochloric Acid SCHEMBL810434 0.85 KMT2A (0.54) KMT2AFABP5FABP7EPHX2CA1
SCHEMBL8612414 0.84 KMT2A (0.54) KMT2AFABP5FABP7EPHX2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115286554-A Preparation method of N-alpha-9-fluorenylmethoxycarbonyl-N-in-tert-butoxycarbonyl-L-tryptophan 常州吉恩药业有限公司 2022-11-04 CN claimed
CN-118307460-A Synthesis method of 9-fluorenylmethyl-N-succinimidyl carbonate 连云港冠昕医药科技有限公司 2024-07-09 CN disclosed
CN-115286554-A Preparation method of N-alpha-9-fluorenylmethoxycarbonyl-N-in-tert-butoxycarbonyl-L-tryptophan 常州吉恩药业有限公司 2022-11-04 CN disclosed
CN-103351324-A Preparation method for 9-fluorenylmethoxycarbonyl succinimide TAICANG HENGYI MEDICINE CHEMICAL MATERIAL FACTORY 2013-10-16 CN disclosed
US-20120135396-A1 Multi-Shell Microspheres With Integrated Chromatographic And Detection Layers For Use In Array Sensors BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-05-31 US disclosed
US-8105849-B2 Integration of fluids and reagents into self-contained cartridges containing sensor elements BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-01-31 US disclosed
US-8101431-B2 Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2012-01-24 US disclosed
US-7781226-B2 Particle on membrane assay system THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-08-24 US disclosed
US-7667051-B2 Method of obtaining urethane-protected N-carboxyanhydrides of alpha amino acids ISOCHEM (FR) 2010-02-23 US disclosed
US-20080299666-A1 Novel Peptide-Based Borono-Lectin (PBL) Sensors UNIVERSITY OF SOUTH CAROLINA (US) 2008-12-04 US disclosed
WO-2005083423-A2 SYSTEM AND METHOD FOR INTEGRATING FLUIDS AND REAGENTS IN SELF-CONTAINED CARTRIDGES CONTAINING PARTICLE AND MEMBRANE SENSOR ELEMENTS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2005-09-09 WO disclosed
US-20050191620-A1 Particle on membrane assay system BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM 2005-09-01 US disclosed
EP-1556397-A1 9A-AZALIDES WITH ANTI-INFLAMMATORY ACTIVITY ZAMBON GROUP S.p.A. (IT) 2005-07-27 EP disclosed
WO-2004072613-A2 MULTI-SHELL MICROSPHERES WITH INTEGRATED CHOMATOGRAPHIC AND DETECTION LAYERS FOR USE IN ARRAY SENSORS BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2004-08-26 WO disclosed
WO-2004039821-A1 9A-AZALIDES WITH ANTI-INFLAMMATORY ACTIVITY ZAMBON GROUP S.P.A. (IT) 2004-05-13 WO disclosed
US-6683189-B1 POLYAMIDE-OLIGONUCLEOTIDE CONJUGATES; NETROPSIN AND DISTAMYCIN A SYNTHESIS CALIFORNIA INSTITUTE OF TECHNOLOGY 2004-01-27 US disclosed
US-6545162-B1 Solid phase biosynthesis of viricide antibiotic CALIFORNIA INSTITUTE OF TECHNOLOGY 2003-04-08 US disclosed
EP-0885189-B9 METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT CALIFORNIA INST OF TECHN (US) 2003-04-02 EP disclosed
EP-0885189-B1 METHOD FOR THE SYNTHESIS OF POLY-PYRROLE AND POLY-IMIDAZOLE CARBOXAMIDES ON A SOLID SUPPORT CALIFORNIA INST OF TECHN (US) 2002-08-28 EP disclosed
US-6090947-A Method for the synthesis of pyrrole and imidazole carboxamides on a solid support CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2000-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080299666-A1 Novel Peptide-Based Borono-Lectin (PBL) Sensors LGALS3BP, LGALS1, BCAP31 KMT2A 4522/4885FABP5 262/4885FABP7 482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.