SCHEMBL3934943

SCHEMBL3934943

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nearest known ligand 0.42

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ PYGB P11216 8/20 0.42
▸ PYGL P06737 3/20 0.41
▸ PYGM P11217 2/20 0.41
▸ MEN1 O00255 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ OGA O60502 1/20 0.35
▸ LMNA P02545 1/20 0.34
▸ GBA1 P04062 1/20 0.34
▸ SLC5A1 P13866 1/20 0.34
▸ SLC5A2 P31639 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29836760 0.84 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL18385978 0.84 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL8507620 0.84 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL16259329 0.78 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL8585884 0.78 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL5703493 0.78 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL28265605 0.78 PYGB (0.41) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL30015863 0.77 MEN1 (0.54) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL7157539 0.77 MEN1 (0.54) PYGBPYGLPYGMMEN1KMT2A
SCHEMBL2785358 0.77 MEN1 (0.54) PYGBPYGLPYGMMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1853217-B1 HAIRCARE USE OF C-GLYCOSIDE DERIVATIVES OREAL (FR) 2009-04-01 — — EP disclosed
US-20080153760-A1 Haircare Use Of C-Glycoside Derivatives L'OREAL (FR) 2008-06-26 — — US disclosed
EP-1853217-A1 HAIRCARE USE OF C-GLYCOSIDE DERIVATIVES L'Oréal (FR) 2007-11-14 — — EP disclosed
WO-2006090307-A1 HAIRCARE USE OF C-GLYCOSIDE DERIVATIVES L'OREAL (FR) 2006-08-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080153760-A1 Haircare Use Of C-Glycoside Derivatives KRT18, CD44, FGF1 PYGB 3968/4885PYGL 3124/4885PYGM 3806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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