Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 7/20 | 0.62 |
| ▸ | BCHE | P06276 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | CASP2 | P42575 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8429394 | 1.00 | BCHE (0.62) | BCHEACHEMEN1MAPTMAPK1 | |
| SCHEMBL3997367 | 0.98 | BCHE (0.65) | BCHEACHE | |
| SCHEMBL4642403 | 0.98 | BCHE (0.65) | BCHEACHE | |
| SCHEMBL1396458 | 0.98 | BCHE (0.65) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL28065825 | 0.91 | BCHE (0.54) | BCHEACHEMEN1MAPTMAPK1 | |
| SCHEMBL14197233 | 0.89 | BCHE (0.56) | BCHEACHE | |
| Bromide SCHEMBL12818867 | 0.87 | ACHE (0.58) | BCHEACHEKMT2ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2834732 | 0.82 | MEN1 (0.46) | BCHEACHEMEN1MAPTMAPK1 | |
| Hydrochloric Acid SCHEMBL10855939 | 0.82 | BCHE (0.94) | BCHEACHEMEN1MAPTMAPK1 | |
| SCHEMBL31207580 | 0.82 | BCHE (0.48) | BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046929-A1 | LIQUID SUPPORT | Henkel AG & Co. KGaA (DE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008012140-A1 | LIQUID SUPPORT | HENKEL AG & CO. KGAA (DE) | 2008-01-31 | — | — | WO | disclosed |
| WO-2007118747-A1 | AQUEOUS CLEANING AGENT CONTAINING PERFUME | HENKEL AG & CO. KGAA (DE) | 2007-10-25 | — | — | WO | disclosed |