Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | GAA | P10253 | 10/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.45 |
| ▸ | MEN1 | O00255 | 9/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.45 |
| ▸ | RELA | Q04206 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945915 | 0.96 | NOX1 (0.50) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3943671 | 0.89 | NOX1 (0.46) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3935496 | 0.88 | NOX1 (0.49) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3935494 | 0.88 | NOX1 (0.49) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3937473 | 0.85 | NOX1 (0.47) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3935339 | 0.85 | CYP1A2 (0.42) | MAPTGAAKMT2AMEN1RAB9A | |
| SCHEMBL3944945 | 0.84 | PABPC1 (0.52) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3945910 | 0.84 | PABPC1 (0.52) | NOX1MAPTGAAKMT2AMEN1 | |
| SCHEMBL3938946 | 0.81 | CYP1A2 (0.43) | MAPTGAAKMT2AMEN1RAB9A | |
| SCHEMBL3939374 | 0.81 | ACHE (0.39) | NOX1MAPTGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1847250-B1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | PROCTER & GAMBLE (US) | 2009-12-23 | — | — | EP | claimed |
| US-7513918-B2 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | claimed |
| EP-1852104-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | claimed |
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | claimed |
| EP-1847250-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | claimed |
| EP-1847250-B1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | PROCTER & GAMBLE (US) | 2009-12-23 | — | — | EP | disclosed |
| US-7513918-B2 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | THE PROCTER & GAMBLE COMPANY (US) | 2009-04-07 | — | — | US | disclosed |
| EP-1852104-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-11-07 | — | — | EP | disclosed |
| WO-2007119228-A2 | AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES | THE PROCTER & GAMBLE COMPANY (US) | 2007-10-25 | — | — | WO | disclosed |
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | WELLA OPERATIONS US, LLC | 2007-10-25 | — | — | US | disclosed |
| EP-1847250-A1 | Agents for colouring keratin fibres comprising zwitterionic azomethine dyes | Wella Aktiengesellschaft (DE) | 2007-10-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070245501-A1 | Agents for coloring keratin fibers comprising zwitterionic azomethine dyes | KRT18, IK, RARG | NOX1 1352/4885MAPT 3818/4885GAA 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.