SCHEMBL3935595

SCHEMBL3935595

Cc1sc(=NN=Cc2cc[n+](CCCS(=O)(=O)[O-])cc2)n(C)c1C

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PABPC1 P11940 1/20 0.37
EIF4H Q15056 1/20 0.37
CTDSP1 Q9GZU7 1/20 0.37
MAPT P10636 7/20 0.35
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
ALDH1A1 P00352 7/20 0.33
ACHE P22303 2/20 0.33
THRB P10828 2/20 0.33
RECQL P46063 2/20 0.33
KDM4E B2RXH2 5/20 0.32
RXFP1 Q9HBX9 1/20 0.32
NPC1 O15118 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
LMNA P02545 1/20 0.32
RAB9A P51151 1/20 0.32
HPGD P15428 2/20 0.31
POLB P06746 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3935589 1.00 PABPC1 (0.37) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3933999 0.97 MAPT (0.34) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3933994 0.97 MAPT (0.34) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3935205 0.90 PABPC1 (0.34) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3935204 0.90 PABPC1 (0.34) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3935603 0.89 ACHE (0.34) MAPTMEN1KMT2AALDH1A1ACHE
SCHEMBL3934928 0.87 MEN1 (0.32) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3934925 0.87 MEN1 (0.32) PABPC1EIF4HCTDSP1MAPTMEN1
SCHEMBL3934003 0.86 MEN1 (0.34) MAPTMEN1KMT2AALDH1A1ACHE
SCHEMBL3934045 0.84 MAPT (0.38) PABPC1EIF4HCTDSP1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1847250-B1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes PROCTER & GAMBLE (US) 2009-12-23 EP claimed
US-7513918-B2 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes THE PROCTER & GAMBLE COMPANY (US) 2009-04-07 US claimed
EP-1852104-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-11-07 EP claimed
WO-2007119228-A2 AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES THE PROCTER & GAMBLE COMPANY (US) 2007-10-25 WO claimed
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes WELLA OPERATIONS US, LLC 2007-10-25 US claimed
EP-1847250-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-10-24 EP claimed
EP-1847250-B1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes PROCTER & GAMBLE (US) 2009-12-23 EP disclosed
US-7513918-B2 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes THE PROCTER & GAMBLE COMPANY (US) 2009-04-07 US disclosed
EP-1852104-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-11-07 EP disclosed
WO-2007119228-A2 AGENTS FOR COLOURING KERATIN FIBRES COMPRISING ZWITTERIONIC AZOMETHINE DYES THE PROCTER & GAMBLE COMPANY (US) 2007-10-25 WO disclosed
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes WELLA OPERATIONS US, LLC 2007-10-25 US disclosed
EP-1847250-A1 Agents for colouring keratin fibres comprising zwitterionic azomethine dyes Wella Aktiengesellschaft (DE) 2007-10-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070245501-A1 Agents for coloring keratin fibers comprising zwitterionic azomethine dyes KRT18, IK, RARG PABPC1 3524/4885EIF4H 4790/4885CTDSP1 4156/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.