SCHEMBL3935787

SCHEMBL3935787

CCCCCCCCCCCCCCCCC(C(=O)OCC(C)C)c1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
ALDH1A1 P00352 3/20 0.46
ASAH1 Q13510 1/20 0.46
ACER2 Q5QJU3 1/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TSHR P16473 1/20 0.44
NAAA Q02083 2/20 0.43
POLB P06746 1/20 0.43
LMNA P02545 1/20 0.42
GPR88 Q9GZN0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2290208 0.94 POLB (0.48) ALDH1A1ASAH1ACER2NPC1RAB9A
SCHEMBL2294572 0.88 ALDH1A1 (0.49) ALDH1A1SMN1; SMN2TSHRGPR88
SCHEMBL4886826 0.87 MMP8 (0.48) PRSS1PRSS2PRSS3ALDH1A1ASAH1
SCHEMBL28066882 0.87 MMP8 (0.48) PRSS1PRSS2PRSS3ALDH1A1ASAH1
SCHEMBL8818975 0.87 MMP8 (0.48) PRSS1PRSS2PRSS3ALDH1A1ASAH1
SCHEMBL29289205 0.86 SLC22A1 (0.49) ALDH1A1ASAH1ACER2NPC1RAB9A
SCHEMBL3929627 0.85 NPC1 (0.56) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL11296489 0.85 NPC1 (0.56) ALDH1A1NPC1RAB9ASMN1; SMN2TSHR
SCHEMBL21357881 0.85 MMP8 (0.47) PRSS1PRSS2PRSS3ALDH1A1ASAH1
SCHEMBL15124223 0.85 MMP8 (0.47) PRSS1PRSS2PRSS3ALDH1A1ASAH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481157-B2 Melt extruded fibers and methods of making the same 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-07-09 US disclosed
EP-2038457-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M Innovative Properties Company (US) 2009-03-25 EP disclosed
US-7476352-B2 Lubricated flow fiber extrusion 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-01-13 US disclosed
US-20080003430-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M INNOVATIVE PROPERTIES COMPANY 2008-01-03 US disclosed
WO-2008002724-A1 PARTICULATE-LOADED POLYMER FIBERS AND EXTRUSION METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-01-03 WO disclosed
US-20070154708-A1 MELT EXTRUDED FIBERS AND METHODS OF MAKING THE SAME 3M INOVATIVE PROPERTIES COMPANY 2007-07-05 US disclosed
EP-1753898-A1 LUBRICATED FLOW FIBER EXTRUSION 3M Innovative Properties Company (US) 2007-02-21 EP disclosed
WO-2005116308-A1 LUBRICATED FLOW FIBER EXTRUSION 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-12-08 WO disclosed
US-20050258562-A1 Lubricated flow fiber extrusion 3M INNOVATIVE PROPERTIES COMPANY 2005-11-24 US disclosed
US-4519909-A HOMOGENEOUS, THREE-DIMENSIONAL POLYMER STRUCTURE AKZONA INCORPORATED (US) 1985-05-28 US disclosed
US-4247498-A THERMOPLASTICS AKZONA INCORPORATED (US) 1981-01-27 US disclosed