Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 10/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | INSR | P06213 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15859165 | 0.83 | INSR (0.35) | ALDH1A1ALDH3A1ALDH1A3MAPTCNR2 | |
| SCHEMBL3932935 | 0.83 | CNR2 (0.34) | MAPTCNR2INSRLTB4R | |
| SCHEMBL12180551 | 0.82 | APP (0.52) | ALDH1A1MAPTAPPLTB4R | |
| SCHEMBL20625203 | 0.78 | HIF1A (0.35) | ALDH1A1MAPTHIF1AEPAS1 | |
| SCHEMBL21243809 | 0.78 | HIF1A (0.35) | MAPTLTB4RHIF1AEPAS1 | |
| SCHEMBL31030240 | 0.78 | APP (0.45) | APP | |
| SCHEMBL31030239 | 0.78 | APP (0.45) | APP | |
| SCHEMBL19615830 | 0.74 | DPP4 (0.40) | ALDH1A1MAPTL3MBTL1HIF1AEPAS1 | |
| SCHEMBL19614811 | 0.74 | GPR35 (0.32) | MAPTHIF1AEPAS1 | |
| SCHEMBL28044579 | 0.73 | GPR35 (0.34) | MAPTHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507840-B2 | Acceptor compounds useful for making hyperpolarizable organic chromophores | UNIVERSITY OF WASHINGTON (US) | 2009-03-24 | — | — | US | disclosed |
| US-7029606-B2 | Hyperpolarizable organic chromophores | UNIVERSITY OF WASHINGTON (US) | 2006-04-18 | — | — | US | disclosed |
| US-20050179013-A1 | Hyperpolarizable organic chromophores | UNIVERSITY OF WASHINGTON | 2005-08-18 | — | — | US | disclosed |
| EP-1305305-A4 | HYPERPOLARIZABLE ORGANIC CHROMOPHORES | UNIV WASHINGTON (US) | 2005-07-20 | — | — | EP | disclosed |
| EP-1305305-A1 | HYPERPOLARIZABLE ORGANIC CHROMOPHORES | The University of Washington (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6555027-B2 | For use in electro-optic modulators, signal processing and telecommunications | PACIFIC WAVE INDUSTRIES, INC. | 2003-04-29 | — | — | US | disclosed |
| US-20020084446-A1 | Hyperpolarizable organic chromophores | UNITED STATES AIR FORCE | 2002-07-04 | — | — | US | disclosed |
| US-6361717-B1 | RING-LOCKED STRUCTURE; HEAT RESISTANT AND OPTICALLY TRANSPARENT AT TELECOMMUNICATION WAVELENGTHS; USED IN SIGNAL DETECTION/PROCESSING AND TELECOMMUNICATIONS | PACIFIC WAVE INDUSTRIES, INC. | 2002-03-26 | — | — | US | disclosed |
| US-20020027220-A1 | Second-order nonlinear optical chromophores containing dioxine and/or bithiophene as conjugate bridge and devices incorporating the same | MACOM TECHNOLOGY SOLUTIONS HOLDINGS, INC. | 2002-03-07 | — | — | US | disclosed |
| WO-2002008215-A1 | HYPERPOLARIZABLE ORGANIC CHROMOPHORES | UNIVERSITY OF WASHINGTON (US) | 2002-01-31 | — | — | WO | disclosed |