Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 1.00 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933677 | 0.87 | FAAH (0.77) | FAAHP2RY1MKNK1TRPV1 | |
| SCHEMBL4872158 | 0.84 | FAAH (0.73) | FAAHMKNK1TRPV1 | |
| SCHEMBL3943345 | 0.83 | FAAH (0.70) | FAAHMKNK1 | |
| SCHEMBL2849779 | 0.82 | FAAH (0.70) | FAAHMKNK1TRPV1 | |
| SCHEMBL3938384 | 0.80 | FAAH (0.67) | FAAHP2RY1MKNK1 | |
| SCHEMBL3936220 | 0.79 | FAAH (1.00) | FAAHMKNK1 | |
| SCHEMBL3939145 | 0.78 | FAAH (0.81) | FAAHTRPV1 | |
| SCHEMBL3932027 | 0.77 | FAAH (1.00) | FAAHMKNK1 | |
| SCHEMBL5777548 | 0.75 | FAAH (0.61) | FAAH | |
| SCHEMBL3933423 | 0.75 | FAAH (0.87) | FAAHMKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |