Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 7/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | BRS3 | P32247 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 5/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936059 | 0.83 | FAAH (1.00) | FAAHMKNK1 | |
| SCHEMBL3941123 | 0.82 | FAAH (0.86) | FAAH | |
| SCHEMBL3936220 | 0.81 | FAAH (1.00) | FAAHTP53MAPTBRS3MKNK1 | |
| SCHEMBL3933677 | 0.81 | FAAH (0.77) | FAAHMKNK1 | |
| SCHEMBL3932027 | 0.81 | FAAH (1.00) | FAAHBRS3MKNK1 | |
| SCHEMBL5777548 | 0.79 | FAAH (0.61) | FAAHLMNASMN1; SMN2USP2TSHR | |
| SCHEMBL3939066 | 0.79 | FAAH (0.82) | FAAHTP53MAPT | |
| SCHEMBL3938384 | 0.78 | FAAH (0.67) | FAAHMKNK1 | |
| SCHEMBL3935343 | 0.78 | FAAH (0.89) | FAAH | |
| SCHEMBL1549789 | 0.76 | FAAH (0.56) | FAAHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |