Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 8/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393612 | 1.00 | AKR1C3 (0.47) | AKR1C3CYP1A2APEX1CA1CA2 | |
| SCHEMBL397625 | 0.85 | CA12 (0.47) | AKR1C3APEX1CA1CA2MAPT | |
| SCHEMBL397623 | 0.85 | CA12 (0.47) | AKR1C3APEX1CA1CA2MAPT | |
| SCHEMBL396301 | 0.84 | CA12 (0.47) | AKR1C3APEX1CA1CA2MMP1 | |
| SCHEMBL396299 | 0.84 | CA12 (0.47) | AKR1C3APEX1CA1CA2MMP1 | |
| SCHEMBL398252 | 0.84 | AKR1C3 (0.44) | AKR1C3APEX1 | |
| SCHEMBL398251 | 0.84 | AKR1C3 (0.44) | AKR1C3APEX1 | |
| SCHEMBL8812676 | 0.82 | AKR1C3 (0.52) | AKR1C3APEX1TSHR | |
| SCHEMBL4803011 | 0.82 | AKR1C3 (0.52) | AKR1C3APEX1AKR1C2AKR1C1 | |
| SCHEMBL396807 | 0.81 | CA12 (0.58) | AKR1C3APEX1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-2105298-A1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | Fujifilm Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |