SCHEMBL396807

SCHEMBL396807

CCCNS(=O)(=O)c1ccccc1C=C(C)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 0.58
CA9 Q16790 6/20 0.58
RECQL P46063 1/20 0.44
AKR1C3 P42330 1/20 0.41
LMNA P02545 1/20 0.38
GAA P10253 1/20 0.38
POLB P06746 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
EPHX2 P34913 1/20 0.37
APEX1 P27695 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL396804 1.00 CA12 (0.58) CA12CA9RECQLAKR1C3LMNA
SCHEMBL397449 0.92 CA12 (0.60) CA12CA9RECQLAKR1C3LMNA
SCHEMBL397452 0.92 CA12 (0.60) CA12CA9RECQLAKR1C3LMNA
SCHEMBL396299 0.89 CA12 (0.47) CA12CA9AKR1C3LMNACA1
SCHEMBL396301 0.89 CA12 (0.47) CA12CA9AKR1C3LMNACA1
SCHEMBL393614 0.81 AKR1C3 (0.47) AKR1C3CA1CA2APEX1
SCHEMBL393612 0.81 AKR1C3 (0.47) AKR1C3CA1CA2APEX1
SCHEMBL397623 0.79 CA12 (0.47) CA12CA9AKR1C3GAAPOLB
SCHEMBL397625 0.79 CA12 (0.47) CA12CA9AKR1C3GAAPOLB
SCHEMBL398251 0.78 AKR1C3 (0.44) AKR1C3APEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8101332-B2 Negative-working lithographic printing plate precursor and method of lithographic printing using same FUJIFILM CORPORATION (JP) 2012-01-24 US disclosed
US-20090246688-A1 NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME FUJIFILM CORPORATION (JP) 2009-10-01 US disclosed
EP-2105298-A1 Negative-working lithographic printing plate precursor and method of lithographic printing using same Fujifilm Corporation (JP) 2009-09-30 EP disclosed