Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 6/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL396299 | 1.00 | CA12 (0.47) | CA12CA9AKR1C3ALDH1A1LMNA | |
| SCHEMBL396807 | 0.89 | CA12 (0.58) | CA12CA9AKR1C3LMNACA1 | |
| SCHEMBL396804 | 0.89 | CA12 (0.58) | CA12CA9AKR1C3LMNACA1 | |
| SCHEMBL397449 | 0.87 | CA12 (0.60) | CA12CA9AKR1C3ALDH1A1LMNA | |
| SCHEMBL397452 | 0.87 | CA12 (0.60) | CA12CA9AKR1C3ALDH1A1LMNA | |
| SCHEMBL393612 | 0.84 | AKR1C3 (0.47) | AKR1C3CA1CA2MMP1MMP2 | |
| SCHEMBL393614 | 0.84 | AKR1C3 (0.47) | AKR1C3CA1CA2MMP1MMP2 | |
| SCHEMBL397623 | 0.81 | CA12 (0.47) | CA12CA9AKR1C3ALDH1A1CA1 | |
| SCHEMBL397625 | 0.81 | CA12 (0.47) | CA12CA9AKR1C3ALDH1A1CA1 | |
| SCHEMBL398252 | 0.80 | AKR1C3 (0.44) | AKR1C3ALDH1A1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101332-B2 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | FUJIFILM CORPORATION (JP) | 2012-01-24 | — | — | US | disclosed |
| US-20090246688-A1 | NEGATIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR AND METHOD OF LITHOGRAPHIC PRINTING USING SAME | FUJIFILM CORPORATION (JP) | 2009-10-01 | — | — | US | disclosed |
| EP-2105298-A1 | Negative-working lithographic printing plate precursor and method of lithographic printing using same | Fujifilm Corporation (JP) | 2009-09-30 | — | — | EP | disclosed |