⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL340835 | 1.00 | — | — | |
| SCHEMBL685448 | 1.00 | — | — | |
| SCHEMBL28617956 | 0.89 | ARG1 (0.58) | — | |
| SCHEMBL36935 | 0.85 | ARG1 (0.61) | — | |
| SCHEMBL36934 | 0.85 | ARG1 (0.61) | — | |
| SCHEMBL36933 | 0.85 | ARG1 (0.61) | — | |
| SCHEMBL29393779 | 0.85 | ARG1 (0.61) | — | |
| SCHEMBL29378137 | 0.85 | ARG1 (0.61) | — | |
| SCHEMBL7211047 | 0.82 | NOS2 (0.41) | — | |
| Hydrochloric Acid SCHEMBL11112802 | 0.82 | GSR (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4337247-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-06-29 | — | — | US | claimed |
| US-20230391828-A1 | REGULATORS OF CELL DIVISION | TECHNISCHE UNIVERSITAT DRESDEN (DE) | 2023-12-07 | — | — | US | disclosed |
| US-20230220033-A1 | GLP-1 AGONIST POLYPEPTIDE COMPOUND AND SALT THEREOF, SYNTHESIS METHOD THEREFOR AND USE THEREOF | SINOPEP-ALLSINO BIOPHARMACEUTICAL CO., LTD. (CN) | 2023-07-13 | — | — | US | disclosed |
| CN-115677482-A | Synthesis method of chiral alpha-hydroxy acid | 上海吉奉生物科技有限公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-4108682-A1 | GLP-1 AGONIST POLYPEPTIDE COMPOUND AND SALT THEREOF, SYNTHESIS METHOD THEREFOR AND USE THEREOF | Sinopep-Allsino Biopharmaceutical Co., Ltd. (CN) | 2022-12-28 | — | — | EP | disclosed |
| EP-3981784-A1 | REGULATORS OF CELL DIVISION | Technische Universität Dresden (DE) | 2022-04-13 | — | — | EP | disclosed |
| US-20120329770-A1 | CEPHALOSPORIN DERIVATIVES USEFUL AS BETA-LACTAMASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | DMITRIENKO GARY IGOR (CA) | 2012-12-27 | — | — | US | disclosed |
| US-7560227-B2 | Biomarkers of vulnerable atherosclerotic plaques and methods of use | UNIVERSITY OF MASSACHUSETTS (US) | 2009-07-14 | — | — | US | disclosed |
| US-20070207507-A1 | Biomarkers of vulnerable atherosclerotic plaques and methods of use | UNIVERSITY OF MASSACHUSETTS (US) | 2007-09-06 | — | — | US | disclosed |
| WO-2006093973-A2 | BIOMARKERS OF VULNERABLE A THEROSCLEROTIC PLAQUES AND METHODS OF USE | UNIVERSITY OF MASSACHUSETTS (US) | 2006-09-08 | — | — | WO | disclosed |
| US-5578470-A | USING CYSTEINE | NEDERLANDSE ORGANISATIE VOOR TOEGEPAST (NL) | 1996-11-26 | — | — | US | disclosed |
| US-5496928-A | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0495963-A4 | IMPROVED HYPOGLYCEMICS | — | 1993-09-01 | — | — | EP | disclosed |
| EP-0555537-A2 | Endothelin antagonistic substance | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| EP-0495963-A1 | IMPROVED HYPOGLYCEMICS | AMYLIN PHARMACEUTICALS, INC. (US) | 1992-07-29 | — | — | EP | disclosed |
| WO-1992003148-A1 | IMPROVED HYPOGLYCEMICS | AMYLIN CORPORATION (US) | 1992-03-05 | — | — | WO | disclosed |
| US-4337247-A | ANALGESICS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0005248-B1 | TETRAPEPTIDEHYDRAZIDE DERIVATIVES AND PROCESS FOR THEIR PREPARATION | Takeda Chemical Industries, Ltd. (JP) | 1982-03-24 | — | — | EP | disclosed |
| EP-0031567-A2 | Tetrapeptidesemicarbazide derivatives and their production and use | Takeda Chemical Industries, Ltd. (JP) | 1981-07-08 | — | — | EP | disclosed |
| US-4277394-A | ANALGESICS, ANTIDIARRHEA, TREATMENT OF MENTAL DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1981-07-07 | — | — | US | disclosed |