Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3552993 | 1.00 | HTR4 (0.51) | HTR4DRD4 | |
| SCHEMBL3540611 | 0.93 | HTR4 (0.55) | HTR4DRD4 | |
| SCHEMBL3936908 | 0.89 | USP30 (0.47) | — | |
| SCHEMBL3540628 | 0.89 | USP30 (0.47) | — | |
| SCHEMBL19175394 | 0.84 | RIPK2 (0.44) | — | |
| SCHEMBL3538922 | 0.84 | HTR4 (0.47) | HTR4DRD4 | |
| SCHEMBL3942580 | 0.84 | HTR4 (0.47) | HTR4DRD4 | |
| SCHEMBL11557104 | 0.84 | HTR4 (0.72) | HTR4DRD4 | |
| SCHEMBL3542078 | 0.82 | HTR4 (0.72) | HTR4DRD4 | |
| SCHEMBL1781337 | 0.81 | ACKR3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2046793-A2 | FUSED PYRIMIDO COMPOUNDS | AstraZeneca AB (SE) | 2009-04-15 | — | — | EP | disclosed |
| WO-2008040951-A1 | COMPOUNDS | ASTRAZENECA AB (SE) | 2008-04-10 | — | — | WO | disclosed |
| WO-2008003958-A2 | FUSED PYRIMIDO COMPOUNDS | ASTRAZENECA AB (SE) | 2008-01-10 | — | — | WO | disclosed |