SCHEMBL3936702

SCHEMBL3936702

Nc1c(S(=O)(=O)O)ccc(O)c1O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NQO1 P15559 1/20 0.45
AURKA O14965 1/20 0.44
AURKB Q96GD4 1/20 0.44
HSD17B10 Q99714 3/20 0.44
ALDH1A1 P00352 3/20 0.44
COMT P21964 1/20 0.41
LDHA P00338 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TTR P02766 1/20 0.38
NT5E P21589 3/20 0.38
LMNA P02545 1/20 0.37
HPGD P15428 1/20 0.37
HIF1A Q16665 1/20 0.37
TSHR P16473 1/20 0.37
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10881024 0.84 AURKA (0.46) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL27881048 0.81 TTR (0.46) NQO1AURKAAURKBHSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL11264863 0.81 NQO1 (0.44) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL8755118 0.81 AURKA (0.43) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL669153 0.79 COMT (0.44) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL29373949 0.79 COMT (0.44) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL6812998 0.79 ALDH1A1 (0.40) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL11053840 0.79 AURKA (0.39) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL31256 0.77 COMT (0.43) NQO1AURKAAURKBHSD17B10ALDH1A1
SCHEMBL29373188 0.77 COMT (0.43) NQO1AURKAAURKBHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7476494-B2 Silver halide photosensitive material and image-forming method using the same FUJIFILM CORPORATION (JP) 2009-01-13 US disclosed
US-20080026333-A1 Silver halide photosensitive material and image-forming method using the same FUJIFILM CORPORATION 2008-01-31 US disclosed
US-7186500-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2007-03-06 US disclosed
US-6924091-B2 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. (JP) 2005-08-02 US disclosed
US-6824968-B2 IMPROVED COLOR REPRODUCTION, AND PARTICULARLY TO A COLOR REVERSAL PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL WHICH IS SUPERIOR IN SKIN COLOR REPRODUCTION FUJI PHOTO FILM CO., LTD. (JP) 2004-11-30 US disclosed
US-20040175662-A1 Silver halide photographic lightsensitive material FUJI PHOTO FILM CO., LTD. 2004-09-09 US disclosed
US-20040081927-A1 Silver halide color reversal photographic light-sensitive material FUJI PHOTO FILM CO., LTD 2004-04-29 US disclosed
US-20030068590-A1 Highly sensitive, low-fogging FUJI PHOTO FILM CO., LTD. 2003-04-10 US disclosed
US-6544725-B2 High-speed FUJI PHOTO FILM CO., LTD. (JP) 2003-04-08 US disclosed
US-6479230-B1 TABULAR SILVER HALIDE GRAIN PHOTOGRAPHIC EMULSION HAVING AN ASPECT RATIO OF 2 OR MORE FUJI PHOTO FILM CO., LTD. (JP) 2002-11-12 US disclosed
US-20020146653-A1 Lightsensitive silver halide photographic emulsion, silver halide photographic lightsensitive material containing the same, and method of enhancing sensitivity of lightsensitive silver halide photographic emulsion FUJIFILM CORPORATION (JP) 2002-10-10 US disclosed