Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
| ▸ | PPARG | P37231 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393674 | 1.00 | CYP3A4 (0.35) | CYP3A4CYP2C9RECQLMEN1KMT2A | |
| SCHEMBL395535 | 0.73 | PPARA (0.37) | ALOX5PPARGLMNA | |
| SCHEMBL392854 | 0.72 | — | — | |
| SCHEMBL390379 | 0.69 | KDM4E (0.40) | MEN1KMT2ALMNA | |
| SCHEMBL10348055 | 0.67 | KMT2A (0.63) | CYP2C9MEN1KMT2ALMNAAKR1C3 | |
| SCHEMBL263163 | 0.64 | CYP3A4 (0.58) | CYP3A4CYP2C9RECQLMEN1KMT2A | |
| SCHEMBL393742 | 0.62 | ALDH1A1 (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL6144649 | 0.62 | CYP3A4 (0.54) | CYP3A4CYP2C9RECQLMEN1KMT2A | |
| SCHEMBL390167 | 0.62 | LMNA (0.48) | MEN1KMT2ALMNA | |
| SCHEMBL389124 | 0.62 | ALDH1A1 (0.53) | CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101590-B2 | 9-aminocarbonylsubstituted derivatives of glycylcyclines | WYETH LLC (US) | 2012-01-24 | — | — | US | disclosed |