Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17653858 | 0.84 | SYK (0.52) | SYKSMN1; SMN2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL3925099 | 0.81 | SYK (0.45) | SYKSMN1; SMN2MAPK1POLBMBOAT4 | |
| SCHEMBL27573575 | 0.77 | MBOAT4 (0.40) | SYKLMNAMBOAT4 | |
| SCHEMBL941980 | 0.77 | CYP4F2 (0.49) | SMN1; SMN2LMNACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3928478 | 0.75 | KCNQ3 (0.47) | SYKSMN1; SMN2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL7447762 | 0.75 | MAPK1 (0.49) | SYKSMN1; SMN2MAPK1ALDH1A1L3MBTL1 | |
| SCHEMBL21503712 | 0.75 | KCNH2 (0.40) | SMN1; SMN2LMNAMAPTMBOAT4KDM4E | |
| SCHEMBL5803365 | 0.75 | KCNH2 (0.40) | SMN1; SMN2LMNAMAPTMBOAT4KDM4E | |
| SCHEMBL18647595 | 0.74 | MBOAT4 (0.42) | SYKMBOAT4 | |
| SCHEMBL3936587 | 0.74 | MAPK1 (0.48) | SYKSMN1; SMN2MAPK1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |
| WO-2009007418-A1 | NOVEL BRONCHODILATING ISOQUINOLINE AMIDES | RESPIRATORIUS AB (SE) | 2009-01-15 | — | — | WO | disclosed |