Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17967278 | 0.84 | MKNK1 (0.54) | MAPTNPC1RAB9AGFERDAO | |
| SCHEMBL3937519 | 0.84 | DAO (0.45) | MAPTNPC1RAB9AGFERDAO | |
| SCHEMBL3947733 | 0.84 | COMT (0.49) | MAPTNPC1RAB9AGFERDAO | |
| SCHEMBL3940488 | 0.82 | HRH4 (0.47) | MAPTNPC1RAB9AGFERCYP19A1 | |
| SCHEMBL3947954 | 0.81 | TAAR1 (0.51) | NPC1RAB9ADAOTAAR1MPO | |
| SCHEMBL4016450 | 0.80 | DYRK1A (0.58) | MAPTNPC1RAB9AGFERDAO | |
| SCHEMBL3940325 | 0.78 | DAO (0.50) | MAPTNPC1RAB9AGFERDAO | |
| SCHEMBL4009916 | 0.77 | NOS1 (0.42) | MAPTNPC1RAB9AGFER | |
| SCHEMBL24622020 | 0.75 | PTGS1 (0.40) | DAOTAAR1PTGS1PTGS2DHFR | |
| SCHEMBL4018767 | 0.75 | NPC1 (0.39) | MAPTNPC1RAB9AGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009016410-A2 | CHEMICAL COMPOUNDS 831 | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | WO | disclosed |