Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 7/20 | 0.71 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.71 |
| ▸ | CHRM4 | P08173 | 13/20 | 0.67 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.64 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599853 | 0.89 | CHRM2 (0.60) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3946316 | 0.87 | CHRM4 (0.69) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3944672 | 0.84 | CHRM4 (0.71) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL18825863 | 0.83 | CHRM2 (1.00) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL2974298 | 0.82 | CHRM2 (0.58) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3946020 | 0.82 | ACHE (0.62) | CHRM4 | |
| SCHEMBL20556233 | 0.81 | CHRM2 (1.00) | CHRM2CHRM1CHRM4 | |
| SCHEMBL29432449 | 0.81 | CHRM4 (1.00) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL29432095 | 0.81 | CHRM4 (1.00) | CHRM2CHRM1CHRM4CHRM5CHRM3 | |
| SCHEMBL3937456 | 0.81 | CHRM4 (0.68) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |