Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 3/20 | 0.71 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.66 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.66 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.66 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938442 | 0.86 | CHRM4 (0.66) | CHRM4CHRM2CHRM1CHRM5CHRM3 | |
| SCHEMBL3946020 | 0.85 | ACHE (0.62) | CHRM4ACHE | |
| SCHEMBL3938460 | 0.84 | CHRM2 (0.71) | CHRM4CHRM2CHRM1CHRM5CHRM3 | |
| SCHEMBL3937456 | 0.84 | CHRM4 (0.68) | CHRM4ACHE | |
| SCHEMBL29432003 | 0.83 | CHRM4 (1.00) | CHRM4CHRM2CHRM1ACHE | |
| SCHEMBL3937233 | 0.81 | MEN1 (0.60) | ACHESIGMAR1 | |
| SCHEMBL3939254 | 0.81 | CHRM4 (0.57) | CHRM4CHRM2ACHE | |
| SCHEMBL22719864 | 0.81 | SIGMAR1 (0.76) | ACHESIGMAR1 | |
| SCHEMBL2976065 | 0.81 | CHRM4 (0.56) | CHRM4CHRM2CHRM1CHRM5CHRM3 | |
| SCHEMBL23993013 | 0.80 | CHRM2 (1.00) | CHRM4CHRM2CHRM1CHRM5CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |
| EP-1720550-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | Sanofi-Aventis (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005089759-A1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI-AVENTIS (FR) | 2005-09-29 | — | — | WO | disclosed |