⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29521082 | 0.86 | — | — | |
| SCHEMBL6545218 | 0.85 | NPC1 (0.33) | — | |
| Water SCHEMBL8997397 | 0.81 | PTGS2 (0.33) | — | |
| SCHEMBL3938132 | 0.80 | — | — | |
| SCHEMBL14306684 | 0.76 | — | — | |
| SCHEMBL27684687 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL14100435 | 0.71 | SIGMAR1 (0.39) | — | |
| SCHEMBL3945347 | 0.70 | — | — | |
| SCHEMBL13901144 | 0.68 | — | — | |
| SCHEMBL19419869 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 124 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119876055-A | Alkene reductase mutant and application thereof in preparation of buvaracetam intermediate | 华东理工大学 | 2025-04-25 | — | — | CN | claimed |
| CN-118706997-A | Resolution and detection method of chiral lactone enantiomer | 广州质量监督检测研究院 | 2024-09-27 | — | — | CN | claimed |
| CN-114751849-B | Preparation method of brivaracetam and intermediate compound | 四川奥邦古得药业有限公司 | 2024-03-22 | — | — | CN | claimed |
| CN-117658956-A | Preparation method of chiral (R) -4-n-propyl-dihydrofuran-2 (3H) -ketone | 新天地医药技术研究院(郑州)有限公司 | 2024-03-08 | — | — | CN | claimed |
| CN-117603118-A | Preparation method of brivaracetam | 重庆天地药业有限责任公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117004663-A | Method for synthesizing (R) -4-propyldihydrofuran-2 (3 hydrogen) -ketone | 上海颐碳化学科技有限公司 | 2023-11-07 | — | — | CN | claimed |
| CN-116874449-A | (R) -4-propyl-dihydrofuran-2-one and purification method and application thereof | 四川奥邦古得药业有限公司 | 2023-10-13 | — | — | CN | claimed |
| CN-109852644-B | Method for preparing intermediate of brivaracetam | 弈柯莱生物科技(上海)股份有限公司 | 2023-04-07 | — | — | CN | claimed |
| CN-115340510-B | Preparation method of brivaracetam intermediate | 天津辰欣药物研究有限公司 | 2023-01-24 | — | — | CN | claimed |
| CN-115466233-A | Synthetic method of brivaracetam intermediate (R) -4-propyl-dihydrofuran-2-ketone | 合肥立方制药股份有限公司 | 2022-12-13 | — | — | CN | claimed |
| CN-114989061-A | Preparation method of brivaracetam | 江苏同禾药业有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-114751849-A | Preparation method of brivaracetam and intermediate compound | 成都栩哲医药科技有限公司 | 2022-07-15 | — | — | CN | claimed |
| CN-113125585-B | Method for detecting R-4-propyl-dihydrofuran-2-ketone or/and related substances thereof | 成都百裕制药股份有限公司 | 2022-05-24 | — | — | CN | claimed |
| CN-108503610-B | A kind of preparation method of optically pure (R) -4- n-propyl-dihydrofuran -2 (3H) -one | 北京艾百诺医药股份有限公司 | 2019-09-13 | — | — | CN | claimed |
| CN-108503610-A | A kind of preparation method of optically pure (R) -4- n-propyls-dihydrofuran -2 (3H) -one | 北京艾百诺医药股份有限公司 | 2018-09-07 | — | — | CN | claimed |
| EP-2046147-B1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2013-05-01 | — | — | EP | claimed |
| US-20090311403-A1 | Method of Using Organic Compounds | GIVAUDAN SA (CH) | 2009-12-17 | — | — | US | claimed |
| CN-101494999-A | Method for using organic compound | GIVAUDAN SA (CH) | 2009-07-29 | — | — | CN | claimed |
| EP-2046147-A1 | METHOD OF USING ORGANIC COMPOUNDS | Givaudan SA (CH) | 2009-04-15 | — | — | EP | claimed |
| WO-2008011742-A1 | METHOD OF USING ORGANIC COMPOUNDS | GIVAUDAN SA (CH) | 2008-01-31 | — | — | WO | claimed |