Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.74 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.40 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4019421 | 0.92 | FAAH (0.70) | FAAHTRPV1CCNE2CCNE1CDK2 | |
| SCHEMBL4019416 | 0.92 | FAAH (0.70) | FAAHTRPV1CCNE2CCNE1CDK2 | |
| SCHEMBL3939127 | 0.91 | FAAH (0.72) | FAAHTRPV1CCNE2CCNE1CDK2 | |
| SCHEMBL3937880 | 0.86 | FAAH (0.74) | FAAHTRPV1CDK2TNFGRM4 | |
| SCHEMBL3931765 | 0.85 | FAAH (0.79) | FAAHTRPV1GRM4HTR7HTR6 | |
| SCHEMBL4012669 | 0.85 | FAAH (0.79) | FAAHTRPV1CCNE2CCNE1CDK2 | |
| SCHEMBL3933752 | 0.85 | FAAH (0.89) | FAAH | |
| SCHEMBL3936220 | 0.85 | FAAH (1.00) | FAAHTP53MAPT | |
| SCHEMBL3935343 | 0.83 | FAAH (0.89) | FAAH | |
| SCHEMBL3937615 | 0.83 | FAAH (1.00) | FAAHHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |