Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 3/20 | 0.42 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSA | P10619 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL5999442 | 0.86 | CYP17A1 (0.51) | IDO1TDO2ALDH1A1MAPTHTT | |
| SCHEMBL20721735 | 0.85 | HTR2A (0.50) | HTR2AHRH1LMNATDP1TAAR1 | |
| SCHEMBL8120556 | 0.82 | SIGMAR1 (0.46) | IDO1TDO2ALDH1A1NPSR1HTR2A | |
| SCHEMBL17802362 | 0.81 | HTR2A (0.63) | ALDH1A1HTR2AHRH1LMNATDP1 | |
| Ammonia Solution, Strong SCHEMBL5998613 | 0.80 | KCNA5 (0.44) | LMNA | |
| SCHEMBL17295946 | 0.80 | IDO1 (0.49) | IDO1TDO2ALDH1A1HTR2ACTSA | |
| SCHEMBL3902718 | 0.80 | HTR2A (0.68) | IDO1TDO2HTR2AHRH1TAAR1 | |
| SCHEMBL54346 | 0.80 | HTR2A (0.59) | HTR2AHRH1LMNATDP1TAAR1 | |
| SCHEMBL18426652 | 0.79 | ALDH1A1 (0.43) | IDO1TDO2ALDH1A1MAPTHTT | |
| SCHEMBL11241805 | 0.78 | IDO1 (0.47) | IDO1TDO2ALDH1A1HTR2AHRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118251379-A | Iron death inhibitor and use thereof | 学校法人自治医科大学 | 2024-06-25 | — | — | CN | disclosed |
| CN-115820094-B | Water-based polyurethane coating and preparation method thereof | 山东奔腾漆业股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| WO-2009010480-A1 | 1-{2-[(DIPHENYL)AMINO]-ETHYL}-PIPERIDINE-4-CARBOXYLIC ACID BENZYLAMIDE DERIVATIVES AND RELATED COMPOUNDS AS CCR5 AGONISTS FOR THE TREATMENT OF IMMUNE AND INFLAMMATORY DISEASES | EUROSCREEN S.A. (BE) | 2009-01-22 | — | — | WO | disclosed |
| EP-1786816-A1 | SPIROHYDANTOIN COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY | Virochem Pharma Inc. (CA) | 2007-05-23 | — | — | EP | disclosed |
| WO-2005023810-A1 | SPIROHYDANTOIN COMPOUNDS AND METHODS FOR THE MODULATION OF CHEMOKINE RECEPTOR ACTIVITY | VIROCHEM PHARMA INC. (CA) | 2005-03-17 | — | — | WO | disclosed |