Glycerin

Glycerin

SCHEMBL394035

CCCCCCCCCCCCCCCCOC(=O)CCCCCCCCCCC.OCC(O)CO

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.73
DUSP3 P51452 1/20 0.73
MEN1 O00255 1/20 0.73
KMT2A Q03164 1/20 0.73
LMNA P02545 1/20 0.73
DGKA P23743 2/20 0.67
MAPT P10636 2/20 0.57
PRSS1 P07477 1/20 0.56
PRSS2 P07478 1/20 0.56
PRSS3 P35030 1/20 0.56
NAAA Q02083 1/20 0.56
DNM1 Q05193 1/20 0.56
PRKCA P17252 1/20 0.55
PRKCE Q02156 1/20 0.55
PRKCQ Q04759 1/20 0.55
PRKCD Q05655 1/20 0.55
MAPK1 P28482 1/20 0.54
HTR2C P28335 1/20 0.54
CNR2 P34972 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cetyl Palmitate SCHEMBL28216712 1.00 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL14562870 1.00 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL7523298 1.00 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL27302948 1.00 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL7895803 1.00 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL27567967 1.00 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL27600324 0.97 KDM4E (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL8378713 0.93 KDM4E (0.69) KDM4EDUSP3MEN1KMT2ALMNA
Glycerin SCHEMBL28228192 0.93 LMNA (0.73) KDM4EDUSP3MEN1KMT2ALMNA
Cetyl Palmitate SCHEMBL6241713 0.92 KDM4E (0.88) KDM4EDUSP3MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9084821-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2015-07-21 US disclosed
US-20130251763-A1 TRANSDERMAL COMPOSITIONS MICRODERMIS CORPORATION (US) 2013-09-26 US disclosed
US-8536228-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2013-09-17 US disclosed
US-20120022165-A1 TRANSDERMAL COMPOSITIONS MICRODERMIS CORPORATION (US) 2012-01-26 US disclosed
US-8101163-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2012-01-24 US disclosed
US-7893285-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2011-02-22 US disclosed
US-7888393-B2 Transdermal compositions MICRODERMIS CORPORATION (US) 2011-02-15 US disclosed
US-20100227929-A1 TRANSDERMAL COMPOSITIONS DRS. SOLUTIONS, LLC (US) 2010-09-09 US disclosed
US-20100203005-A1 TRANSDERMAL COMPOSITIONS DRS. SOLUTIONS, LLC (US) 2010-08-12 US disclosed
US-20100197795-A1 TRANSDERMAL COMPOSITIONS DRS. SOLUTIONS, LLC (US) 2010-08-05 US disclosed
US-20040122105-A1 Transdermal compositions DRSS GLOBAL, LLC 2004-06-24 US disclosed
WO-2004026259-A2 TRANSDERMAL COMPOSITIONS BETTLE GRISCOM III (US) 2004-04-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130251763-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, FFAR3 KDM4E 4067/4885DUSP3 1289/4885MEN1 2596/4885
US-20100203005-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, FFAR3 KDM4E 4067/4885DUSP3 1289/4885MEN1 2596/4885
US-20100197795-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, DGKG KDM4E 4108/4885DUSP3 1386/4885MEN1 2399/4885
US-20120022165-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, FFAR3 KDM4E 4067/4885DUSP3 1289/4885MEN1 2596/4885
US-20100227929-A1 TRANSDERMAL COMPOSITIONS S100A10, TMSB10, FFAR3 KDM4E 4067/4885DUSP3 1289/4885MEN1 2596/4885
US-20040122105-A1 Transdermal compositions S100A10, DGKG, COX6C KDM4E 3526/4885DUSP3 1479/4885MEN1 4028/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.