Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL998385 | 1.00 | PNP (0.78) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982283 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5790133 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL976991 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982273 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23982169 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL15623873 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL976990 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL1470361 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL8712178 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7531312-B2 | Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor | TAS PROJECT CO., LTD. (JP) | 2009-05-12 | — | — | US | disclosed |
| US-20060099634-A1 | Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor | ECOLOGICAL TECHNOLOGY RESEARCH, LTD. (JP) | 2006-05-11 | — | — | US | disclosed |
| US-20030186260-A1 | Simple method of biologically evaluating natural and artificial chemicals by using dna injury index and apparatus therefor | ECOLOGICAL TECHNOLOGY RESEARCH, LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1267162-A1 | SIMPLE METHOD OF BIOLOGICALLY EVALUATING NATURAL AND ARTIFICIAL CHEMICALS BY USING DNA INJURY INDEX AND APPARATUS THEREFOR | Ecological Technology Research, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |