Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 1/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.78 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.78 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.78 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.78 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.55 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.55 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.55 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.55 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.55 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940787 | 1.00 | PNP (0.78) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982283 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5790133 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL976991 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982273 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23982169 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL15623873 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL976990 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL1470361 | 0.90 | LMNA (0.76) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL8712178 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190100553-A1 | DIRECT ACTIVITY ASSAYS AND COMPOSITIONS FOR NUCLEOTIDE POOL SANITIZING ENZYMES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-04-04 | — | — | US | claimed |
| WO-2017180309-A1 | DIRECT ACTIVITY ASSAYS AND COMPOSITIONS FOR NUCLEOTIDE POOL SANITIZING ENZYMES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-10-19 | — | — | WO | claimed |
| US-20190100553-A1 | DIRECT ACTIVITY ASSAYS AND COMPOSITIONS FOR NUCLEOTIDE POOL SANITIZING ENZYMES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2019-04-04 | — | — | US | disclosed |
| WO-2017180309-A1 | DIRECT ACTIVITY ASSAYS AND COMPOSITIONS FOR NUCLEOTIDE POOL SANITIZING ENZYMES | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2017-10-19 | — | — | WO | disclosed |
| US-9096893-B2 | Methods for analysis of nucleic acid molecules during amplification reactions | HOLOGIC, INC. (US) | 2015-08-04 | — | — | US | disclosed |
| CN-102301000-B | Compositions and methods for analysis of nucleic acid molecules during amplification reactions | HOLOGIC INC | 2015-04-29 | — | — | CN | disclosed |
| WO-2014158628-A1 | COMPOSITIONS AND METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES | HOLOGIC, INC. (US) | 2014-10-02 | — | — | WO | disclosed |
| US-20140057259-A1 | METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES DURING AMPLIFICATION REACTIONS | HOLOGIC, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| EP-2274448-B1 | COMPOSITIONS AND METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES DURING AMPLIFICATION REACTIONS | HOLOGIC INC (US) | 2013-09-18 | — | — | EP | disclosed |
| CN-102301000-A | Compositions And Methods For Analysis Of Nucleic Acid Molecules During Amplification Reactions | — | 2011-12-28 | — | — | CN | disclosed |
| EP-2274448-A2 | COMPOSITIONS AND METHODS FOR ANALYSIS OF NUCLEIC ACID MOLECULES DURING AMPLIFICATION REACTIONS | HOLOGIC, INC. (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7282333-B2 | Methods and compositions for nucleic acid analysis | PROMEGA CORPORATION (US) | 2007-10-16 | — | — | US | disclosed |
| US-20070134666-A1 | Simultneous analytical method for oxidatively damaged guanine compound and concentration correcting substance thereof, and analyzer used for this analytical method | KASAI HIROSHI | 2007-06-14 | — | — | US | disclosed |
| US-20070122839-A1 | Methods and compositions for nucleic acid analysis | PROMEGA CORPORATION | 2007-05-31 | — | — | US | disclosed |
| US-20060099634-A1 | Simplified biological evaluation method of natural and artificial chemicals by using DNA injury index and apparatus therefor | ECOLOGICAL TECHNOLOGY RESEARCH, LTD. (JP) | 2006-05-11 | — | — | US | disclosed |
| US-20050123921-A1 | Method of purifying oxidatively injured guanine nucleoside, method of measuring the same and analyzer for the embodiment thereof | KASAI HIROSHI (JP) | 2005-06-09 | — | — | US | disclosed |
| US-20050084894-A1 | Methods and compositions for nucleic acid analysis | PROMEGA CORPORATION | 2005-04-21 | — | — | US | disclosed |
| EP-1484609-A1 | METHOD OF PURIFYING OXIDATIVELY INJURED GUANINE NUCLEOSIDE, METHOD OF MEASURING THE SAME AND ANALYZER FOR THE EMBODIMENT THEREOF | Kasai, Hiroshi (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-20030186260-A1 | Simple method of biologically evaluating natural and artificial chemicals by using dna injury index and apparatus therefor | ECOLOGICAL TECHNOLOGY RESEARCH, LTD. (JP) | 2003-10-02 | — | — | US | disclosed |
| EP-1267162-A1 | SIMPLE METHOD OF BIOLOGICALLY EVALUATING NATURAL AND ARTIFICIAL CHEMICALS BY USING DNA INJURY INDEX AND APPARATUS THEREFOR | Ecological Technology Research, Ltd. (JP) | 2002-12-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190100553-A1 | DIRECT ACTIVITY ASSAYS AND COMPOSITIONS FOR NUCLEOTIDE POOL SANITIZING ENZYMES | UNG, WRN, MPG | PNP 16/4885LMNA 1264/4885TP53 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.