Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.49 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.48 |
| ▸ | BCL9 | O00512 | 7/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | SLC13A5 | Q86YT5 | 1/20 | 0.41 |
| ▸ | USP5 | P45974 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941097 | 0.93 | PTGDR2 (0.51) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL4110985 | 0.92 | SMN1; SMN2 (0.48) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL3941700 | 0.89 | BCL9 (0.54) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL3941279 | 0.88 | BCL9 (0.46) | CNR1BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL3928445 | 0.88 | BCL9 (0.47) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL3941517 | 0.86 | MAPT (0.55) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL14366755 | 0.86 | MEN1 (0.48) | BCL9CTNNB1MEN1KMT2AAKR1C3 | |
| SCHEMBL3932070 | 0.86 | ALDH1A1 (0.50) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL3929084 | 0.86 | MAPT (0.55) | PTGDR2BCL9CTNNB1MEN1KMT2A | |
| SCHEMBL3938045 | 0.86 | MAPT (0.55) | PTGDR2BCL9CTNNB1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044017-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |
| WO-2007146838-A2 | SUBSTITUTED PHENYL ACETIC ACIDS AS DP-2 ANTAGONISTS | ICOS CORPORATION (US) | 2007-12-21 | — | — | WO | disclosed |