Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 17/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2158770 | 0.88 | CCR1 (0.74) | CCR1KCNH2 | |
| SCHEMBL2158768 | 0.88 | CCR1 (0.74) | CCR1KCNH2 | |
| SCHEMBL3941668 | 0.86 | CCR1 (0.78) | CCR1KCNH2 | |
| SCHEMBL3007118 | 0.80 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3007113 | 0.80 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3943809 | 0.80 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3949634 | 0.76 | CCR1 (0.61) | CCR1KCNH2 | |
| SCHEMBL3945220 | 0.75 | CCR1 (0.78) | CCR1NPC1OPRM1 | |
| SCHEMBL3946317 | 0.75 | CCR1 (0.78) | CCR1ALDH1A1SMN1; SMN2OPRM1 | |
| SCHEMBL3941358 | 0.75 | CCR1 (0.76) | CCR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |