Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 19/20 | 0.78 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945220 | 0.89 | CCR1 (0.78) | CCR1ACE2 | |
| SCHEMBL3946317 | 0.89 | CCR1 (0.78) | CCR1ACE2 | |
| SCHEMBL2160762 | 0.88 | CCR1 (1.00) | CCR1KCNH2 | |
| SCHEMBL10291923 | 0.88 | CCR1 (1.00) | CCR1KCNH2 | |
| SCHEMBL3943809 | 0.87 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3007113 | 0.87 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3007118 | 0.87 | CCR1 (1.00) | CCR1 | |
| SCHEMBL3949634 | 0.86 | CCR1 (0.61) | CCR1ACE2KCNH2 | |
| SCHEMBL3940996 | 0.86 | CCR1 (0.67) | CCR1KCNH2 | |
| SCHEMBL2160090 | 0.85 | CCR1 (1.00) | CCR1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049486-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2009-04-22 | — | — | EP | disclosed |
| WO-2007092681-A2 | PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-08-16 | — | — | WO | disclosed |