Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.73 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ULK1 | O75385 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942409 | 0.89 | FAAH (0.77) | FAAHKMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL3936894 | 0.87 | FAAH (0.79) | FAAHTRPV1ALDH1A1LMNAMAPK1 | |
| SCHEMBL3931443 | 0.87 | FAAH (0.77) | FAAHSLC22A12TRPV1ALDH1A1LMNA | |
| SCHEMBL3934364 | 0.87 | FAAH (0.77) | FAAHMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL3938565 | 0.87 | FAAH (0.77) | FAAHTRPV1GBA1ALDH1A1LMNA | |
| SCHEMBL3939171 | 0.87 | FAAH (0.77) | FAAHGBA1ALDH1A1LMNAMAPK1 | |
| SCHEMBL3943266 | 0.86 | FAAH (0.82) | FAAHTRPV1GBA1ALPLHSD11B1 | |
| SCHEMBL4013257 | 0.86 | FAAH (0.68) | FAAHSLC22A12TRPV1ULK1ALDH1A1 | |
| SCHEMBL3936607 | 0.86 | FAAH (0.68) | FAAHMEN1KMT2AALDH1A1ALPL | |
| SCHEMBL3943921 | 0.85 | FAAH (0.75) | FAAHALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |