Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.68 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 2/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3930939 | 0.90 | FAAH (0.73) | FAAHMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL3939171 | 0.89 | FAAH (0.77) | FAAHALDH1A1TSHRALPLPPARG | |
| SCHEMBL3943266 | 0.88 | FAAH (0.82) | FAAHCNR1CNR2ALPL | |
| SCHEMBL3943262 | 0.88 | FAAH (0.76) | FAAHCNR2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3936957 | 0.87 | FAAH (0.75) | FAAHCNR2ALDH1A1TSHRALPL | |
| SCHEMBL3932159 | 0.86 | FAAH (0.79) | FAAHCNR1 | |
| SCHEMBL3941389 | 0.86 | FAAH (0.73) | FAAHMEN1ALDH1A1KMT2AALPL | |
| SCHEMBL3934462 | 0.85 | FAAH (0.72) | FAAHCNR2ALDH1A1ALPL | |
| SCHEMBL3931640 | 0.85 | FAAH (0.73) | FAAHCNR2ALDH1A1TSHRALPL | |
| SCHEMBL3942824 | 0.85 | FAAH (0.71) | FAAHCNR2ALDH1A1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |