SCHEMBL3941652

SCHEMBL3941652

COc1ccc(C#Cc2cc(OC)c(OC(C)C)cc2OC(=O)CI)cc1OC(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACACB O00763 6/20 0.44
PDE4B Q07343 4/20 0.38
PDE4A P27815 3/20 0.35
PDE4C Q08493 3/20 0.35
PDE4D Q08499 3/20 0.35
ALDH1A1 P00352 1/20 0.35
MAPT P10636 1/20 0.35
MAPK1 P28482 1/20 0.35
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3943880 0.98 ACACB (0.41) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL6075043 0.80 ACACB (0.43) ACACB
SCHEMBL3941664 0.77 ACACB (0.42) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL3952203 0.75 ACACB (0.40) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL3946740 0.74 ALDH1A1 (0.41) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL3236478 0.72 ACACB (0.42) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL3941671 0.72 ALDH1A1 (0.41) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL3268072 0.71 PTGDR2 (0.32) ACACBPTGESFFAR1
SCHEMBL5746992 0.71 PDE4B (0.37) ACACBPDE4BPDE4APDE4CPDE4D
SCHEMBL5031027 0.71 PDE4B (0.44) ACACBPDE4BPDE4APDE4CPDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423486-B1 None US disclosed
EP-1041433-B1 Heat-developable photosensitive material and method for forming image using the same FUJIFILM CORP (JP) 2009-11-25 EP disclosed
EP-0990946-B1 Heat-developable photosensitive material FUJIFILM CORP (JP) 2009-09-09 EP disclosed
EP-0957398-B1 Thermographic recording element FUJIFILM CORP (JP) 2009-08-05 EP disclosed
US-7557118-B2 Preparation of fused polycyclic alkaloids by ring closure of azomethine ylides, novel compounds thereof and their use as chemotherapeutic agents THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2009-07-07 US disclosed
EP-1063566-B1 A method for preparing non-photo-sensitive fatty acid silver salt grain FUJIFILM CORP (JP) 2009-06-10 EP disclosed
EP-1069469-B1 Thermally processed image forming material FUJIFILM CORP (JP) 2008-03-19 EP disclosed
EP-1020760-B1 Heat developable image recording material FUJIFILM CORP (JP) 2007-11-14 EP disclosed
EP-1026545-B1 Heat developable photosensitive material FUJIFILM CORP (JP) 2007-09-26 EP disclosed
US-20070212656-A1 PHOTOTHERMOGRAPHIC MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-09-13 US disclosed
EP-0869391-A1 Heat-developable photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1998-10-07 EP disclosed
EP-0838722-A2 Photothermographic material, novel 2,3-dihydrothiazole derivative, and photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-04-29 EP disclosed
EP-0834767-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 1998-04-08 EP disclosed
EP-0829753-A1 Photographic silver halide photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 1998-03-18 EP disclosed
EP-0807850-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 1997-11-19 EP disclosed
EP-0805376-A2 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 1997-11-05 EP disclosed
EP-0803765-A1 Preparation of photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
EP-0803764-A1 Photothermographic material and method for making FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
EP-0803766-A1 Photothermographic material FUJI PHOTO FILM CO., LTD. (JP) 1997-10-29 EP disclosed
US-5654134-A CHEMICAL RIPENING INPRESENCE OF A LABILE TELLURIUM OR SELENIUM SENSITIZER FUJI PHOTO FILM CO., LTD. (JP) 1997-08-05 US disclosed