Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.37 |
| ▸ | PDE4A | P27815 | 2/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 5/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.32 |
| ▸ | TUBB | P07437 | 1/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.32 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3952203 | 0.89 | ACACB (0.40) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL3941664 | 0.89 | ACACB (0.42) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL5747442 | 0.82 | ALDH1A1 (0.39) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL3946740 | 0.73 | ALDH1A1 (0.41) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL3941671 | 0.73 | ALDH1A1 (0.41) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL3943880 | 0.71 | ACACB (0.41) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL5746990 | 0.71 | ALDH1A1 (0.37) | PDE4BACACBACHEALDH1A1MAPT | |
| SCHEMBL3941652 | 0.71 | ACACB (0.44) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL3236478 | 0.69 | ACACB (0.42) | PDE4BPDE4APDE4CPDE4DACACB | |
| SCHEMBL3662959 | 0.67 | ALDH1A1 (0.43) | PDE4BACACBACHEHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613635-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004073598-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2004-09-02 | — | — | WO | disclosed |