Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A1 | P04798 | 2/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 5/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | PTAFR | P25105 | 2/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942276 | 1.00 | CYP1A1 (0.48) | CYP1A1CYP1B1KDRCYP1A2CYP3A4 | |
| SCHEMBL3942282 | 1.00 | CYP1A1 (0.48) | CYP1A1CYP1B1KDRCYP1A2CYP3A4 | |
| SCHEMBL3939639 | 0.89 | MEN1 (0.44) | CYP1A1CYP1B1KDRCYP3A4CYP2C19 | |
| SCHEMBL3939647 | 0.89 | MEN1 (0.44) | CYP1A1CYP1B1KDRCYP3A4CYP2C19 | |
| SCHEMBL3939644 | 0.89 | MEN1 (0.44) | CYP1A1CYP1B1KDRCYP3A4CYP2C19 | |
| SCHEMBL4088036 | 0.88 | ESR1 (0.42) | CYP1A1CYP1B1KDRMAOBNPC1 | |
| SCHEMBL4088046 | 0.88 | ESR1 (0.42) | CYP1A1CYP1B1KDRMAOBNPC1 | |
| SCHEMBL4088042 | 0.88 | ESR1 (0.42) | CYP1A1CYP1B1KDRMAOBNPC1 | |
| SCHEMBL4097921 | 0.88 | CYP1A1 (0.56) | CYP1A1CYP1B1KDRMAOBPTAFR | |
| SCHEMBL4097918 | 0.88 | CYP1A1 (0.56) | CYP1A1CYP1B1KDRMAOBPTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2009-08-13 | — | — | US | disclosed |
| EP-2050734-A1 | PENTADIENAMIDE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090203667-A1 | PENTADIENAMIDE DERIVATIVES | PRMT1, REN, NGLY1 | CYP1A1 916/4885CYP1B1 382/4885KDR 2225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.