Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM4 | P08173 | 7/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2974338 | 0.83 | KDM4E (0.44) | CHRM4SIGMAR1KDM4EPOLBTSHR | |
| SCHEMBL3940604 | 0.82 | KCNH2 (0.52) | CHRM4ACHE | |
| SCHEMBL3946467 | 0.78 | ACHE (0.52) | CHRM4ACHECHRM2 | |
| SCHEMBL3936620 | 0.77 | HTR2A (0.56) | CHRM4 | |
| SCHEMBL3945816 | 0.75 | CXCR4 (0.59) | CHRM4KDM4EPOLBALDH1A1ACHE | |
| SCHEMBL3939254 | 0.73 | CHRM4 (0.57) | CHRM4ACHECHRM2 | |
| SCHEMBL5709492 | 0.72 | CHRM4 (0.61) | CHRM4CHRM2 | |
| SCHEMBL3939238 | 0.71 | CHRM4 (0.53) | CHRM4POLBACHECHRM2 | |
| SCHEMBL3941799 | 0.71 | CHRM4 (0.53) | CHRM4POLBSMN1; SMN2ALDH1A1ACHE | |
| SCHEMBL3946388 | 0.70 | CHRM4 (0.55) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |