Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3946467 | 0.88 | ACHE (0.52) | ACHECHRM4MAOAMAOB | |
| SCHEMBL2972067 | 0.81 | CXCR4 (0.49) | CXCR4ACHECHRM4MAOAMAOB | |
| SCHEMBL3937038 | 0.81 | CHRM4 (0.52) | ACHECHRM4MAOAMAOB | |
| SCHEMBL3946396 | 0.81 | ACHE (0.55) | ACHECHRM4 | |
| SCHEMBL3940604 | 0.81 | KCNH2 (0.52) | ACHECHRM4 | |
| SCHEMBL3937725 | 0.81 | MAOA (0.52) | ACHECHRM4POLBMAOAMAOB | |
| SCHEMBL3939238 | 0.79 | CHRM4 (0.53) | ACHECHRM4POLBMAOAMAOB | |
| SCHEMBL3941799 | 0.79 | CHRM4 (0.53) | ACHECHRM4POLBMAOAMAOB | |
| SCHEMBL3597886 | 0.78 | CXCR4 (0.71) | CXCR4POLBALDH1A1 | |
| SCHEMBL3937233 | 0.77 | MEN1 (0.60) | ACHEKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | claimed |
| EP-1720550-B1 | DERIVATIVES OF PIPERIDINYLALKYLCARBAMATES, PREPARATION METHOD THEREOF AND USE OF SAME AS FAAH ENZYME INHIBITORS | SANOFI AVENTIS (FR) | 2009-04-15 | — | — | EP | disclosed |