Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3942507 | 0.93 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL13032349 | 0.92 | TRPV4 (0.32) | TRPV4 | |
| SCHEMBL3483265 | 0.82 | — | — | |
| SCHEMBL13032348 | 0.81 | CA2 (0.34) | TRPV4 | |
| SCHEMBL3483950 | 0.80 | CA2 (0.34) | — | |
| SCHEMBL3483260 | 0.79 | — | — | |
| SCHEMBL3483679 | 0.78 | CA2 (0.35) | — | |
| SCHEMBL4213331 | 0.76 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL14942521 | 0.73 | TRPV4 (0.35) | TRPV4 | |
| SCHEMBL13031903 | 0.72 | TRPV4 (0.33) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2049200-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MethylGene Inc. (CA) | 2009-04-22 | — | — | EP | claimed |
| WO-2008073142-A2 | NOVEL INHIBITORS OF BETA-LACTAMASE | MERCK & CO., INC. (US) | 2008-06-19 | — | — | WO | claimed |