Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614071 | 0.79 | MAOA (0.41) | CYP1A2CYP2A6RXFP1NOTUMKMT2A | |
| SCHEMBL5969633 | 0.79 | MAOA (0.41) | CYP1A2CYP2A6RXFP1NOTUMKMT2A | |
| Hydrochloric Acid SCHEMBL30423571 | 0.78 | MAOA (0.39) | CYP1A2CYP2A6RXFP1NOTUMKMT2A | |
| SCHEMBL29366435 | 0.69 | CYP1A2 (1.00) | CYP1A2CYP2A6MAOACFTRGOPC | |
| SCHEMBL77106 | 0.69 | CYP1A2 (1.00) | CYP1A2CYP2A6MAOACFTRGOPC | |
| SCHEMBL29765632 | 0.67 | HPGD (0.59) | CYP1A2CYP2A6NOTUMKMT2ARNASEH1 | |
| SCHEMBL10463768 | 0.66 | CYP1A2 (0.94) | CYP1A2CYP2A6KMT2AMAOACFTR | |
| Ammonia Solution, Strong SCHEMBL13736473 | 0.66 | CYP1A2 (0.94) | CYP1A2CYP2A6MAOACFTRGOPC | |
| SCHEMBL25433262 | 0.66 | SRD5A1 (0.40) | RXFP1NOTUMMAOAMAOB | |
| SCHEMBL25409744 | 0.66 | CYP1A2 (0.39) | CYP1A2CYP2A6RXFP1NOTUMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009020590-A1 | METHODS FOR TREATING LYMPHOMAS IN CERTAIN PATIENT POPULATIONS AND SCREENING PATIENTS FOR SAID THERAPY | CELGENE CORPORATION (US) | 2009-02-12 | — | — | WO | disclosed |