Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29614071 | 1.00 | MAOA (0.41) | MAOAMAOBCYP2A6RXFP1KMT2A | |
| Hydrochloric Acid SCHEMBL30423571 | 0.98 | MAOA (0.39) | MAOAMAOBCYP2A6RXFP1KMT2A | |
| Trifluoroacetic Acid SCHEMBL29148099 | 0.85 | DPP8 (0.38) | NOTUMALDH1A1 | |
| SCHEMBL3943105 | 0.79 | CYP1A2 (0.50) | MAOAMAOBCYP2A6RXFP1KMT2A | |
| SCHEMBL25433262 | 0.73 | SRD5A1 (0.40) | MAOAMAOBRXFP1NOTUMALDH1A1 | |
| SCHEMBL23832541 | 0.72 | KMT2A (0.67) | MAOAMAOBCYP2A6KMT2AMEN1 | |
| SCHEMBL29569183 | 0.72 | KMT2A (0.67) | MAOAMAOBCYP2A6KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL4557636 | 0.71 | KMT2A (0.65) | MAOAMAOBCYP2A6KMT2AMEN1 | |
| SCHEMBL30722457 | 0.71 | HPGD (0.49) | CYP2A6KMT2AMEN1CYP1A2CYP2C9 | |
| SCHEMBL28656618 | 0.69 | KMT2A (0.34) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279910-A | Modulators of BCL6 proteolysis and related methods of use | 阿尔维纳斯运营股份有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116669769-A | Piperidinyl small molecule degradants of HELIOS and methods of use | 达纳－法伯癌症研究所公司 | 2023-08-29 | — | — | CN | disclosed |
| WO-2023143482-A1 | 2-AMINOPYRIMIDINE COMPOUND OR SALT, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海辉启生物医药科技有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-113874016-A | Compound and use thereof | 福宏治疗公司 | 2021-12-31 | — | — | CN | disclosed |
| EP-3183244-A1 | PROCESS FOR MAKING CRYSTALLINE FORM A OF LENALIDOMIDE | Synthon BV (NL) | 2017-06-28 | — | — | EP | disclosed |
| WO-2016026785-A1 | PROCESS FOR MAKING CRYSTALLINE FORM A OF LENALIDOMIDE | SYNTHON B.V. (NL) | 2016-02-25 | — | — | WO | disclosed |
| EP-1567158-A4 | METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS FOR TREATMENT AND MANAGEMENT OF CANCERS AND OTHER DISEASES | CELGENE CORP (US) | 2006-05-17 | — | — | EP | disclosed |
| EP-1567158-A2 | METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS FOR TREATMENT AND MANAGEMENT OF CANCERS AND OTHER DISEASES | CELGENE CORPORATION (US) | 2005-08-31 | — | — | EP | disclosed |
| WO-2004043377-A2 | METHODS AND COMPOSITIONS USING IMMUNOMODULATORY COMPOUNDS FOR TREATMENT AND MANAGEMENT OF CANCERS AND OTHER DISEASES | CELGENE CORPORATION (US) | 2004-05-27 | — | — | WO | disclosed |