1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL3943128

C=C(C=CC(=O)O)C(=O)OC.C=C(Cl)Cl

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.46
ALDH1A1 P00352 5/20 0.39
TSHR P16473 2/20 0.38
TP53 P04637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.38
EGLN3 Q9H6Z9 1/20 0.38
ALOX15 P16050 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
GAA P10253 1/20 0.33
KEAP1 Q14145 1/20 0.32
NFE2L2 Q16236 1/20 0.32
HTT P42858 2/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL36949 0.94 HCAR2 (0.52) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL4611870 0.89 HCAR2 (0.48) HCAR2ALDH1A1TSHRTP53EGLN1
Acrylic Acid SCHEMBL4839392 0.88 HCAR2 (0.46) HCAR2ALDH1A1TSHRTP53EGLN1
Methacrylic Acid SCHEMBL3104275 0.86 ALDH1A1 (0.48) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL1476972 0.86 ALDH1A1 (0.60) HCAR2ALDH1A1TSHRTP53EGLN1
1,1-Dichloroethene SCHEMBL5586489 0.83 ALDH1A1 (0.43) HCAR2ALDH1A1TSHR
Acrylonitrile SCHEMBL8018394 0.81 HCAR2 (0.41) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL6244209 0.80 HCAR2 (0.39) HCAR2ALDH1A1TSHRTP53EGLN1
SCHEMBL5678091 0.80 HCAR2 (0.39) HCAR2ALDH1A1TSHRTP53EGLN1
1,1-Dichloroethene SCHEMBL6373416 0.79 HCAR2 (0.52) HCAR2ALDH1A1TSHRTP53EGLN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7563494-B2 Ink-jet recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2009-07-21 US disclosed
EP-1020760-B1 Heat developable image recording material FUJIFILM CORP (JP) 2007-11-14 EP disclosed
US-20060188811-A1 Planographic printing plate material and printing process KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2006-08-24 US disclosed
EP-1045284-B1 Heat developing method for heat developable image recording material FUJI PHOTO FILM CO LTD (JP) 2005-07-06 EP disclosed
US-20050064339-A1 lithographic plates comprising plastic film sheet supports having hydrophilic layer and an image formation layers containing extender pigments; writing using infrared lasers KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-03-24 US disclosed
US-6613418-B2 Ink-jet recording material and use of the same MITSUBISHI PAPER MILLS LIMITED (JP) 2003-09-02 US disclosed
US-6562561-B1 Dimensional change over time after the heat development can be prevented by using a support which is coated on both sides with undercoat layers comprising a vinylidene chloride copolymer FUJI PHOTO FILM CO., LTD. (JP) 2003-05-13 US disclosed
US-20020182380-A1 Ink-jet recording material MITSUBISHI PAPER MILLS LIMITED (JP) 2002-12-05 US disclosed
EP-0869391-B1 Heat-developable photographic materials FUJI PHOTO FILM CO LTD (JP) 2002-06-26 EP disclosed
US-20020071018-A1 Ink-jet recording material and use of the same MITSUBISHI PAPER MILLS, LIMITED (JP) 2002-06-13 US disclosed
US-4722885-A IMPROVED ADHESION BETWEEN LAYERS FUJI PHOTO FILM CO., LTD. (JP) 1988-02-02 US disclosed
US-4629678-A A SULFUR COMPOUND AS A FINISH ADDITIVE: IMPROVED REVERSE PERFORMANCE; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1986-12-16 US disclosed
US-4556632-A CONTAINING CYAN AZO DYE RELEASING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1985-12-03 US disclosed
US-4533626-A Photographic light-sensitive material with 4-(paranitrophenylazo)naphthol dyes FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US disclosed
US-4533622-A IN ALKALINE PROCESSING SOLUTION FUJI PHOTO FILM CO., LTD. (JP) 1985-08-06 US disclosed
EP-0143310-A2 Color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-06-05 EP disclosed
US-4517286-A STABILITY FUJI PHOTO FILM CO., LTD. (JP) 1985-05-14 US disclosed
EP-0140371-A2 Internal latent image-type direct positive silver halide light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1985-05-08 EP disclosed
US-4255515-A HYDROPHOBIC POLYMER, ANTISTATIC AGENT, PENTAERYTHRITOL FATTY ESTER KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1981-03-10 US disclosed
US-4058649-A POLYPROPYLENE, ACRYLIC OR METHACRYLIC ACID-VINYLIDENE CHLORIDE-ALKYL ACRYLATE TERPOLYMER MOBIL OIL CORPORATION (US) 1977-11-15 US disclosed