1,1-Dichloroethene

1,1-Dichloroethene

SCHEMBL6373416

C=C(C=CC(=O)O)C(=O)OCC.C=C(Cl)Cl

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 6/20 0.52
ALDH1A1 P00352 6/20 0.40
TSHR P16473 3/20 0.40
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.37
GLO1 Q04760 1/20 0.37
CYP2D6 P10635 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
EGLN1 Q9GZT9 2/20 0.35
TP53 P04637 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.33
CASP1 P29466 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL40331 0.94 HCAR2 (0.57) HCAR2ALDH1A1TSHRMAPTNPSR1
Butadiene SCHEMBL11410298 0.89 HCAR2 (0.52) HCAR2ALDH1A1TSHRMAPTNPSR1
Acrylic Acid SCHEMBL11216503 0.89 HCAR2 (0.52) HCAR2ALDH1A1TSHRMAPTNPSR1
Methacrylic Acid SCHEMBL3440748 0.87 HCAR2 (0.50) HCAR2ALDH1A1TSHRMAPTNPSR1
SCHEMBL10933729 0.84 HCAR2 (0.47) HCAR2ALDH1A1TSHRMAPTNPSR1
SCHEMBL8823387 0.84 HCAR2 (0.47) HCAR2ALDH1A1TSHRMAPTNPSR1
1,1-Dichloroethene SCHEMBL7547901 0.83 HCAR2 (0.57) HCAR2ALDH1A1TSHRMAPTNPSR1
Acrylonitrile SCHEMBL9282459 0.83 ALDH1A1 (0.47) HCAR2ALDH1A1TSHRMAPTNPSR1
SCHEMBL770780 0.83 ALDH1A1 (0.48) HCAR2ALDH1A1TSHRMAPTNPSR1
SCHEMBL2866687 0.82 HCAR2 (0.44) HCAR2ALDH1A1TSHRMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050118543-A1 Comprising substrate having thereon light sensitive layer comprising organic silver salt particles, silver halide particles and reducing agent; polyvinylidene chloride layer is provided on substrate and vapor barrier layer comprising latex and wax is provided on outer layer; humidity, blocking resistance KONICA MINOLTA MEDICAL & GRAPHIC, INC. 2005-06-02 US disclosed
US-6093529-A COMPRISING A SUPPORT, A PHOTOTHERMOGRAPHIC IMAGE-FORMING LAYER COMPRISING ORGANIC SILVER SALT, LIGHT-SENSITIVE SILVER HALIDE REDUCING AGENT AND BINDER WITH A PROTECTIVE COATING CONTAINING A POLYVALENT METAL SALT OF PHTHALIC ACID; STORAGE STABILITY FUJI PHOTO FILM CO., LTD. (JP) 2000-07-25 US disclosed
US-5747237-A SUPPORT WITH PREFOGGED DIRECT POSITIVES EMULSION LAYER WITH SILVER HALIDE SOLVENT AND GRAINS, RHODIUM AND RUTHENIUM SALTS FUJI PHOTO FILM CO., LTD. (JP) 1998-05-05 US disclosed
EP-0242853-B1 SILVER HALIDE PHOTOGRAPHIC MATERIAL WITH IMPROVED ANTISTATIC PROPERTIES KONICA CORPORATION (JP) 1992-12-09 EP disclosed
US-5137802-A Overcoating with organosiloxane and nonionic surfactant KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1992-08-11 US disclosed
EP-0242853-A2 Silver halide photographic material with improved antistatic properties KONICA CORPORATION (JP) 1987-10-28 EP disclosed