Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940279 | 0.86 | MAPT (0.48) | MAPTALDH1A1HSD17B10MT-CO2MEN1 | |
| SCHEMBL2566463 | 0.82 | MAPT (0.46) | MAPTALDH1A1HSD17B10KDM4EMT-CO2 | |
| SCHEMBL30889131 | 0.82 | HPGD (0.36) | MAPTALDH1A1HSD17B10KDM4EHPGD | |
| SCHEMBL11902792 | 0.78 | MAPT (0.43) | MAPTMT-CO2MEN1KMT2A | |
| SCHEMBL14637386 | 0.78 | MAPT (0.43) | MAPTKDM4EMT-CO2 | |
| Bicarbonate SCHEMBL9807679 | 0.76 | MAPT (0.51) | MAPTALDH1A1MT-CO2 | |
| SCHEMBL125003 | 0.74 | — | — | |
| SCHEMBL1263005 | 0.74 | HDAC4 (0.38) | ALDH1A1HSD17B10KDM4EHPGDMEN1 | |
| SCHEMBL9298583 | 0.74 | KMT2A (0.43) | MAPTMEN1KMT2A | |
| SCHEMBL25440082 | 0.74 | KMT2A (0.60) | MAPTALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805316-B1 | PROCESS FOR THE PREPARATION OF THE ENANTIOMERIC FORMS OF CIS-3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES EMPLOYING HYDROLASES | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-04-15 | — | — | EP | disclosed |
| EP-1805316-A2 | METHOD FOR PRODUCING THE ENANTIOMER FORMS OF CIS-CONFIGURED 3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES USING HYDROLASES | Sanofi-Aventis Deutschland GmbH (DE) | 2007-07-11 | — | — | EP | disclosed |
| WO-2006015716-A2 | METHOD FOR PRODUCING THE ENANTIOMER FORMS OF CIS-CONFIGURED 3-HYDROXYCYCLOHEXANE CARBOXYLIC ACID DERIVATIVES USING HYDROLASES | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-02-16 | — | — | WO | disclosed |