Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 14/20 | 0.57 |
| ▸ | RAB9A | P51151 | 13/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.54 |
| ▸ | RELA | Q04206 | 3/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689179 | 0.85 | APP (0.71) | APPNPC1RAB9ARXFP1HPGD | |
| Styrene SCHEMBL3943655 | 0.85 | APP (0.58) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL122784 | 0.82 | APP (0.81) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL8889974 | 0.80 | APP (0.79) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL556200 | 0.76 | NPC1 (0.67) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL12887959 | 0.75 | NPC1 (0.55) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL12641772 | 0.75 | APP (0.71) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL12573308 | 0.74 | APP (1.00) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL4871397 | 0.74 | KDM4E (0.69) | APPNPC1RAB9ARXFP1HPGD | |
| SCHEMBL9885482 | 0.74 | APP (0.69) | APPNPC1RAB9ARXFP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050791-B1 | POLYCARBONATE RESIN COMPOSITION AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME | MITSUBISHI GAS CHEMICAL CO (JP) | 2013-10-23 | — | — | EP | disclosed |
| EP-2050791-A1 | POLYCARBONATE RESIN COMPOSITION AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY USING THE SAME | Mitsubishi Gas Chemical Company, Inc. (JP) | 2009-04-22 | — | — | EP | disclosed |