SCHEMBL556200

SCHEMBL556200

CN(C)c1ccc(-c2nnc(-c3cccc(-c4nnc(-c5ccc(N(C)C)cc5)o4)c3)o2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 14/20 0.67
RAB9A P51151 13/20 0.67
KMT2A Q03164 4/20 0.67
APP P05067 2/20 0.67
ALDH1A1 P00352 5/20 0.63
HPGD P15428 4/20 0.63
KDM4E B2RXH2 3/20 0.63
MAPT P10636 3/20 0.63
HSD17B10 Q99714 2/20 0.63
SMN1; SMN2 Q16637 8/20 0.60
MEN1 O00255 3/20 0.60
NFKB1 P19838 3/20 0.60
NFKB2 Q00653 3/20 0.60
RELA Q04206 3/20 0.60
RXFP1 Q9HBX9 2/20 0.60
GAA P10253 2/20 0.60
HCRTR1 O43613 1/20 0.60
CASP3 P42574 1/20 0.60
SENP7 Q9BQF6 1/20 0.60
CA1 P00915 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11938167 0.89 NPC1 (0.56) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL12826704 0.89 NPC1 (0.56) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL6689179 0.89 APP (0.71) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL122784 0.89 APP (0.81) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL8889974 0.87 APP (0.79) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL1250845 0.86 KDM4E (0.73) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL12887959 0.85 NPC1 (0.55) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL12171094 0.84 MYC (0.58) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL12641772 0.81 APP (0.71) NPC1RAB9AKMT2AAPPALDH1A1
SCHEMBL12313134 0.81 NPC1 (0.53) NPC1RAB9AKMT2AAPPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9106057-B2 White-emitting monomolecular compound using excited-state intramolecular proton transfer, organic electroluminescent element and laser device using the same DONGWOO FINE-CHEM CO. LTD. (KR) 2015-08-11 US disclosed
US-8895156-B2 Organic light emitting diode and organic light emitting display having the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-25 US disclosed
US-8895156-B2 Organic light emitting diode and organic light emitting display having the same SAMSUNG DISPLAY CO., LTD. (KR) 2014-11-25 US disclosed
US-8586211-B2 Asymmetrical aryl amine derivative for organic electroluminescence devices, method for preparing same, organic thin film for organic electroluminescence devices and organic electroluminescence device using same DONGWOO FINE-CHEM CO. LTD. (KR) 2013-11-19 US disclosed
US-8569510-B2 White-emitting compounds using excited-state intramolecular proton transfer, organic electroluminescent element and laser material using the same DONGWOO FINE-CHEM CO. LTD. (KR) 2013-10-29 US disclosed
US-8227092-B2 organic electroluminescent device having an emission layer, which is constructed with a host, a phosphorescence emission molecule as a dopant, and receives energy from the host or traps energy directly, and then transfers the energy to the dopant or a fluorescence supporter. SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-07-24 US disclosed
US-8227092-B2 organic electroluminescent device having an emission layer, which is constructed with a host, a phosphorescence emission molecule as a dopant, and receives energy from the host or traps energy directly, and then transfers the energy to the dopant or a fluorescence supporter. SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-07-24 US disclosed
US-8173270-B2 Conducting polymer composition and organic optoelectronic device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-05-08 US disclosed
US-8173270-B2 Conducting polymer composition and organic optoelectronic device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-05-08 US disclosed
US-20120032152-A1 Asymmetrical Aryl Amine Derivative for Organic Electroluminescence Devices, Method for Preparing Same, Organic Thin Film for Organic Electroluminescence Devices and Organic Electroluminescence Device Using Same DONGWOO FINE-CHEM CO. LTD. (KR) 2012-02-09 US disclosed
US-7829205-B2 Organic light emitting device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-09 US disclosed
US-7829205-B2 Organic light emitting device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2010-11-09 US disclosed
US-20080118775-A1 First electrode; an organic layer formed on the first electrode, an emitting layer, an electron transport layer of C60 doped with an organic n-type impurity; and a second electrode formed on the organic layer SAMSUNG SDI CO., LTD. (KR) 2008-05-22 US disclosed
US-20080118775-A1 First electrode; an organic layer formed on the first electrode, an emitting layer, an electron transport layer of C60 doped with an organic n-type impurity; and a second electrode formed on the organic layer SAMSUNG SDI CO., LTD. (KR) 2008-05-22 US disclosed
US-20070187675-A1 Organic light emitting device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2007-08-16 US disclosed
US-20070187675-A1 Organic light emitting device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2007-08-16 US disclosed
US-20070176174-A1 Conducting polymer composition and organic optoelectronic device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-08-02 US disclosed
US-20070176174-A1 Conducting polymer composition and organic optoelectronic device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-08-02 US disclosed
US-20070108893-A1 Organic light emitting device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2007-05-17 US disclosed
US-20070108893-A1 Organic light emitting device SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2007-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120032152-A1 Asymmetrical Aryl Amine Derivative for Organic Electroluminescence Devices, Method for Preparing Same, Organic Thin Film for Organic Electroluminescence Devices and Organic Electroluminescence Device Using Same AOC2, ALKBH2, ALKBH1 NPC1 3437/4885RAB9A 2236/4885KMT2A 287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.