Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.65 |
| ▸ | HPGD | P15428 | 4/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | NPC1 | O15118 | 13/20 | 0.61 |
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.61 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.61 |
| ▸ | RELA | Q04206 | 3/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | CA1 | P00915 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12641772 | 0.98 | APP (0.71) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL8889974 | 0.92 | APP (0.79) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL122784 | 0.90 | APP (0.81) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL12354769 | 0.87 | NPC1 (0.63) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL13231671 | 0.86 | NPC1 (0.79) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL10341190 | 0.85 | NPC1 (0.66) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6015198 | 0.84 | NPC1 (0.83) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL120253 | 0.84 | NPC1 (0.83) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6689179 | 0.83 | APP (0.71) | APPKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL1105473 | 0.82 | ALDH1A1 (0.83) | APPKDM4EALDH1A1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2460788-A1 | METAL COMPLEX, COMPOSITION COMPRISING SAME AND LIGHT-EMITTING ELEMENT USING SAME | Sumitomo Chemical Company, Limited (JP) | 2012-06-06 | — | — | EP | disclosed |